Groundbreaking research.
Community engagement.
Progress.

ACTG is a global clinical trials network that conducts research to improve the management of HIV and its comorbidities; develop a cure for HIV; and innovate treatments for tuberculosis, hepatitis B, and emerging infectious diseases.

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Welcome

The ACTG welcomes investigators from outside our funded Clinical Research Sites to engage with the network. There are many ways to get involved based on your interests and goals and participation in site activities is not required. Opportunities include applying to join scientific committees, submitting new research concepts for potential protocol development, and requesting access to our robust sample and data repositories. Early-career investigators, fellows, postdoctoral researchers, and new faculty are strongly encouraged to get involved and to learn how the ACTG can help support your research goals. Scientific Committees The research conducted by the network is generated through five major Transformative Science Groups (TSGs): Antiretroviral Therapy, HIV Cure, Tuberculosis, Comorbidities, and Viral Hepatitis. These groups are complemented by cross cutting groups focused on Behavioral Science, Women’s Health, Neurology, and Implementation Science. Committee members rotate at regular intervals. Membership applications are solicited annually, and self nominations are welcome and encouraged. These committees review concepts submitted to the network for consideration for development into network clinical trials. The TSG’s also review requests to use samples and data.

ACTG Welcomes New Members to its Network

Network Leaders Express Gratitude 2025

HANC and Network Leadership would like to share the following video messages expressing their gratitude and appreciation to the NIH HIV/AIDS Clinical Trials Network research staff, CABs and community. Thank you for all your immense efforts and contributions.

Our Impact and Reach

Since our founding in 1987, ACTG investigators and sites across four continents have served as major resources for HIV and other infectious disease research, treatment, care, and education in their communities.

47k+

participants

65

sites

15

countries

3k+

trials

Our Trials Locations Worldwide

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Botswana

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Peru

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Zimbabwe

Voices for the Community

Benedict Sandile Khumalo

GCAB Co-Chair

Maureen Phiri

CAB member

Mandisa Jwara

CAB member

Roseline Swartz

CAB member

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8 Trials Currently Enrolling

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