Our Clinical Sites and Trials

Trials Sites

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Trial

Research Area

Duration

Locations

  • A5384: Treatment of Adults and Adolescents with Tuberculous Meningitis

    Study Description A5384 is a trial for people who have or might have tuberculous meningitis (TBM). TBM is an infectious…

    Open and enrolling

    Tuberculosis

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  • A5385: Observational PIC Destination Protocol

    This study is a two-step, non-interventional extension study for individuals participating in another interventional HIV cure trial (parent study) that…

    Open and enrolling

    Treatment Experienced

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  • A5388: Combination HIV-Specific bnAbs Combined with ART Initiation

    Scientists are looking for ways to minimize the distribution of HIV-1 in the body, especially where anti-HIV medications (ART) are…

    Open and enrolling

    Treatment Naïve

    Between 2 and 5 years.

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  • A5409: Novel Regimens for Pulmonary TB

    The standard of care (SOC) treatment of tuberculosis (TB) was developed over 40 years ago, and the treatment is long…

    Open and enrolling

    Tuberculosis

    Participants will be in this study for about 52 weeks. This includes a total of 26 weeks of TB treatment. If assigned to the experimental arm, participants will have 8 weeks of experimental treatment, followed by 18 weeks of SOC treatment. If assigned to the SOC arm, participants will have 26 weeks of SOC treatment.

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  • A5413: Dasatinib for HIV-1 Reservoir Reduction

    To determine if dasatinib is safe and well tolerated in people with HIV, and to see if dasatinib can reduce…

    Open and enrolling

    HIV Cure, Treatment Experienced

    36 weeks

    • Study Treatment: 12 Weeks
    • Follow-up: 24 Weeks

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  • A5424: Menopause and HIV

    Menopausal hormone therapy (MHT) is considered the most effective therapy for vasomotor symptoms (VMS; also known as hot flashes and…

    Open and enrolling

    Treatment Experienced

    Participants will be in this study for approximately 5 months.

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  • A5428: Small Trial of Alendronate Impact on the Reservoir of HIV (STAIR-HIV)

    Though antiretroviral therapy (ART) is very effective at suppressing the HIV virus, it is, however, unable to totally remove it…

    Open and enrolling

    HIV Cure, Treatment Experienced

    Participants will be in this study for about 44 weeks; this includes:

    • 12 weeks for pre-intervention evaluations
    • 24 weeks of study treatment
    • 8 weeks of follow-up after stopping study treatment

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