• Director of Data Management Center Reflects on Nearly Two Decades of Research

    December 16, 2015 pendari Leadership

    Meet Marlene Cooper

    Marlene Cooper, M.S., has been involved in clinical trials data management and related research for 19 years.  She started her work in the field of HIV/AIDS in 1996 as a Project Coordinator for the Ryan White Care Act HIV Needs Assessment for Northeast Ohio while working on her Masters degree in Epidemiology at Case Western Reserve University in Cleveland, OH.  Working in the community, she became interested in the relationship between perceived susceptibility and risk behaviors as well as the need for programs to target underserved populations. Her initial introduction to clinical trials was as a Research Assistant at the Tuberculosis Research Unit at Case Western. However, it was when she relocated back to New York State, where she is originally from, that Marlene began her career at Frontier Science and Technology Research Foundation (FSTRF) focusing exclusively on clinical trials data.  Fast forward nearly twenty years to last December when Marlene was promoted to the position of Director of the ACTG Network Data Management Center at FSTRF.

    In addition to her duties as the Director of the ACTG Data Management Center, Marlene is also the Director of Data Management for the International Maternal Pediatric Adolescent AIDS Clinical Trials (IMPAACT) Network Data Management Center at FSTRF. She is responsible for all data management activities for both networks and ensures that dedicated clinical and laboratory data management, information technology, database operations and programming resources are available for research.  Marlene notes one of the most rewarding aspects of the work she and her colleagues perform is that it often directly impacts treatment guidelines and advances the understanding of how and when to treat individuals living with HIV/AIDS.

    “The results from ACTG clinical trials provide valuable information for clinicians regarding how to effectively manage HIV/AIDS, including co-infections, and gives insight into additional treatment options for hard to treat individuals,” said Marlene. “It’s humbling to think that I’ve played a small role in advancing the research by my work in support of these trials.”

    Marlene considers the ACTG Network a second family to her in many ways and although she has worked in different roles and in different capacities over the years, her relationships with colleagues remains a constant. She has worked with Robert Coombs MD, PhD, ACTG Network Laboratory Principal Investigator, University of Washington, Seattle, since first starting at FSTRF and considers him not only a colleague, but a good friend.

    “I enjoy all the relationships I have made with investigators, laboratory staff, protocol teams and other members of the HIV/AIDS research community,” said Marlene. “My relationship with Dr. Coombs in particular has allowed me to continue to foster my interest in the science of infectious diseases and specifically HIV infection, and how the virus hides in the body, mutates and avoids eradication.”

    Over the years, Marlene has seen a significant shift in technology at FSTRF.  With the move to the internet and cloud-based technology, she has seen the introduction of more commercial software solutions for data management.  At FSTRF, they are constantly looking to improve efficiency and make data more easily and readily available to ACTG Network investigators and statisticians.  In fact, they are currently in the process of transitioning to a commercial Clinical Trials Data Management System for clinical sites, so this is an exciting time for FSTRF and the ACTG Network.

     “Marlene brought to this effort an in-depth understanding of our work garnered through her background in epidemiology, and the knowledge and experience she gained over her 20 years in this field,” said Gregory Pavlov, President and Chief Executive Officer, Frontier Science and Technology Research Foundation. “Coupled with her innate understanding of computing and database concepts and technologies, and her outstanding organizational and communications skills, Marlene has proved to be the ideal person to lead this project that is critical to the long term success of our company.”

    In the future, Marlene plans to continue her work advancing clinical trials data management with new technology and providing high quality data to answer the research questions posed by ACTG Network researchers. She notes that she has learned patience, persistence and hard work pays off and it is exciting to see how far the field has come in the past twenty years; nevertheless, there is still much work to do to expand treatment access and identify a cure.  

    Marlene also has a closing message to others who work in the field of data management:

    “Keep up the exceptional work!  Accurate and quality data collection is critical to the success of our clinical trials and the valuable research conducted across the ACTG Network. The work you perform on a daily basis provides critical information that will help bring us one step closer to a cure for HIV.”

     

  • ACTG Leadership and Operations Center

    July 2, 2012 pendari Leadership

    On June 1, the ACTG Leadership and Operations Center (the LOC), at the Brigham and Women’s Hospital (BWH) in Boston, Massachusetts, will assume responsibility for management of the Network Leadership Group grant. BWH is home to the ACTG Network Principal Investigator (PI), Dr. Daniel Kuritzkes, and to clinical research site 107, one of the longest established in the network. In a month, the hospital will also host the ACTG’s fiscal, grant management, and contracting functions, giving the Network PI more control over the group’s financial operations. The move will help the ACTG keep its place at the forefront of HIV therapeutics research in a rapidly developing and competitive environment; and an enthusiastic and committed team of six has been working closely with staff at Social & Scientific Systems, Inc., and is ready to take charge.

    [The LOC team pictured top, from left to right:
    Sarah Maloney, Project Coordinator
    Angela Rhodes, Financial Analyst
    Haley Salinas, Finance Manager
    Benjamin Raynak, Contracts Specialist
    Stephen Fetters, Grants Administrator
    Lauren Robertson, ACTG Executive Director]

    [Lauren Robertson is pictured above]

    The new ACTG Executive Director, Lauren Robertson, is at its head and is a network veteran. She is a former grants administrator with the Harvard/Partners ACTG Clinical Trials Unit and returned to the network in December with an 8-year track record in research, operations, and grants management. Her capable managers, analysts, and specialists are similarly accomplished with over 20 years of experience in finance and grants management for the network. Some of the staff is transferring to the LOC from other positions at BWH, while others are new hires from the public and private sectors.

    The team will be taking on the management of finances and operations for a research network of 73 research sites and 21 specialty laboratories, spread across four continents, and currently enrolling participants to 25 separate clinical trials. It is an immense task and time-sensitive work that does not forgive errors, but the LOC is ready for it. The LOC team has the enthusiastic support of BWH, believes in the network’s mission, and is happy to be part of one of the world’s largest HIV/AIDS clinical trials networks. In Lauren Robertson’s words: “I’m extremely excited to be back with the ACTG.”

  • Dr. Judith S. Currier

    January 1, 1970 pendari Leadership

    [Spotlight originally posted October, 2010]

    Dr. Currier is Professor of Medicine, Chief, Division of Infectious Diseases and Co-Director of the Center for AIDS Research and Education Center (CARE) at the University of California Los Angeles at UCLA. She is Vice Chair of the NIH sponsored AIDS Clinical Trials Group and is currently the Principal Investigator of the UCLA AIDS Prevention and Treatment Clinical Trials Unit. The unit includes four sites in Los Angeles and is involved in community based prevention, HIV vaccine research and therapeutic clinical trials. Her areas of expertise include evaluating new antiretroviral therapies and treatment for complications associated with HIV infection. She has also led several efforts to expand the study of sex differences in treatment outcomes and to enhance research on women with HIV.

  • Dr. Daniel R. Kuritzkes

    January 1, 1970 pendari Leadership

    [Spotlight originally posted August, 2010]

    Dr. Kuritzkes, Professor of Medicine at Harvard Medical School and Director of AIDS Research, Brigham & Women’s Hospital, was elected by the ACTG Voting Members in December 2009 to lead the ACTG Network as Network Chair/PI and to chair the Executive Committee. He is Director of AIDS Research/Professor of Medicine at Brigham and Women’s Hospital and an ACTG Clinical Trials Unit PI.

    Dr. Kuritzkes has published numerous articles on HIV antiretroviral therapy and has chaired several multicenter studies of HIV therapy. He also has published extensively on the problem of drug resistance in HIV infection and serves on the IAS-USA panel that developed guidelines for drug resistance testing. He has served on numerous NIH committees and chaired the HIV Disease Research Agenda Committee of the Adult AIDS Clinical Trials Group. Dr Kuritzkes is a member of the editorial boards of several journals and serves as an Associate Editor for the Journal of Infectious Diseases.

  • US Honors Women's Role in Research

    January 1, 1970 pendari Leadership

    The AIDS Clinical Trials Group (ACTG) Network would like to acknowledge all of the women and girls who are infected or affected by HIV every day, but especially March 10, National Women and Girls HIV/AIDS Awareness Day in the United States. The ACTG is committed to including women in its clinical trials at every point in the process from development to enrollment to reporting results that include sex comparisons. We appreciate your courage and commitment to continuing this important research so that we can further understand how HIV/AIDS uniquely impacts women and girls.

    Susan E. Cohn, MD, MPH, Investigator at the ACTG’s Northwestern University Clinical Research Site, and Co-Chair of the ACTG Women’s Health Inter-Network Scientific Committee (WHISC), and Cindy Firnhaber, MD, Technical Director of the ACTG’s Clinical HIV Research Unit in Johannesburg, South Africa, and Co-Vice-Chair of the ACTG WHISC.

  • A Call for Applications

    January 1, 1970 pendari Leadership

    In 1996, Kim Smith, MD, MPH, became one of the first two recipients of the AIDS Clinical Trials Group’s (ACTG’s) Minority HIV Investigator Mentoring Program (MHIMP). Now 17 years later, Smith, as Chair of the Network’s Underrepresented Populations Committee (UPC), will help choose the next pair of MHIMP recipients.

    “The ACTG is a place where you can come and do multi-center work on a wide range of HIV research topics that impact minorities including women, Latinos and people of color,” says Smith, the Clinical Research Site (CRS) Leader at Rush University Medical Center. “My time in the program introduced me to every aspect of a clinical trial. I am still conducting studies with the ACTG at Rush and my colleague who was in the program with me is also still in HIV research.”

    The MHIMP program allows a site within the ACTG Network to offer a mentorship to a junior minority investigator with an interest in studying virology, immunology, pharmacology or another aspect of HIV/AIDS research. The award is granted to two participants through the UPC every year. When accepting the award, the recipient agrees to serve on the UPC as well as an ACTG scientific committee or working group.

    The deadline for applications was Friday, March 29, 2013.

    Candice McNeil, MD, MPH, is halfway through her MHIMP award at the ACTG’s Stanford CRS.  She completed graduate training in Epidemiology at University of Miami, where she received an Award of Academic Merit. McNeil earned her medical degree at Wayne State University School of Medicine and completed a primary care residency in Medicine and Pediatrics in the Yale New Haven Health System. She joined Stanford in 2008 for Infectious Diseases fellowship training, where her research interests include infectious diseases in women, genitourinary human papillomavirus infections and screening for cervical and anal carcinoma in high-risk and HIV infected persons.

    “In this difficult funding environment, having support from the MHIMP that allows you to pursue your research interests is priceless,” says McNeil. “The mentorship connections are so helpful as well. Where else can you have access to so many experts to bounce ideas off of?”

    McNeil is also grateful that the award has given her protected time to focus on research work and develop new projects within the ACTG. This is a sentiment past MHIMP participant Jose Castillo-Mancilla, MD, echoes.

    “People you would be embarrassed to even approach before, I can now email with a new idea,” says Castillo-Mancilla, an investigator at the ACTG’s site at the University of Colorado Hospital CRS.

    Originally from Mexico, Castillo-Mancilla knew he wanted to continue further training in the United States. Unfortunately, because of visa limitations, he was not able to get the research opportunities that he wanted right away. Later, he found it difficult to continue down the path he wanted due to a limited background in research.

    Luckily, his colleague and later his MHIMP mentor, Thomas Campbell, MD, CRS Leader at the University of Colorado Hospital, recommended that Castillo-Mancilla apply for the MHIMP award.

    “The award provided the catalyst for Jose to get involved with ACTG research and develop other research ideas,” says Campbell. “Without this, it would have been much harder.”

    “If I had not been awarded the program, none of this would have happened,” adds Castillo-Mancilla. “It validated my efforts to have the ACTG behind me. It allowed me to open up to a world where a lot of doors had been closed in the past.” 

     

     

  • The Advocate & the Academy

    January 1, 1970 pendari Leadership

    On the evening of Thursday, Jan. 10, 2013, longtime AIDS Clinical Trials Group Network Advocate Bill Bahlman faced a daunting decision – attend a dinner for his ACTG site’s New York University’s Community Advisory Board or a party celebrating that just that day How to Survive a Plague received an Oscar nomination for Best Documentary Feature. Bahlman is one of several AIDS activists whose stories are woven together in the film by first time director David France. How To Survive A Plague shows to the world how a group of activists banded together to form ACT UP and demand the U.S. government give them a seat at the table to advocate for research and treatments, from AZT monotherapy to protease cocktails, to stop the thousands of citizens dying from HIV/AIDS in the 1980s.  

    As to the choice of the NYU dinner or the cast and crew party, “I ended up attending the ACTG NYU CAB gathering that night and everyone was surprised by my choice,” Bahlman says with a laugh over the phone from his West Village apartment in New York City. “Two years ago, my CAB presented me with the Quarter Century Award since I helped form the CAB back in 1985. It was also important to be with my fellow CAB members and staff because we were saluting the outgoing Chair Don MacIver. He is the glue that kept the CAB together for many years.”

    A humble statement from a native New Yorker who since the age of 19 has himself been the glue that has held many movements together. He began what was to be one year of community service by joining the Gay Activist Alliance (GAA) in the 1971. He immediately not only planned demonstrations and spoke at colleges and high schools, but also became an ambassador for GAA as Chair of National Gay Movement Committee.

    In 1974, as GAA began to dissolve, Bahlman took a break from the movement to work as a prominent New Wave DJ in the New York club scene. In 1985 he returned to movement work with GLAAD, the Gay and Lesbian Alliance Against Defamation, and The Coalition For Lesbian & Gay Rights. When HIV/AIDS began disproportionately taking the lives of his friends in the mid-1980’s, Bahlman founded the first treatment activist group The Lavender Hill Mob. The “Mob” met in his West Village apartment. 

    The core of the Lavender Hill Mob was Marty Robinson, Henry Yeager and Bahlman. He credits Robinson with realizing that “it didn’t matter whether you were homeless on the streets or Rock Hudson, if we didn’t have effective treatments, we all were going to die.” After a year of intensive activism by the Mob, the time was right for greater numbers to become involved and ACT UP was born. 

    How To Survive A Plague features interviews with Bahlman and archival video he shot at many ACT UP demonstrations as well as his brand of “on the scene reporting” for the first ever weekly comprehensive LGBT television news show appropriately named “Out in the 80’s.”

    “Plague Director David France and the editors did such an amazing job pulling the ACT UP story together for the big screen,” Bahlman says. “It’s brilliant what he choreographed. Adding to the team’s professionalism, the sound editing was done at George Lucas’ Skywalker Studios, which was donated for free. The musical score was pulled together by people who were behind the ‘Red Hot & Blue’ series of CD fundraisers.”

    The movie has been sweeping the independent and mainstream awards circuit throughout the United States and Europe. How to Survive a Plague has gone from being among the more than 130 Oscar qualifying documentaries in December to a short list of 15 possible contenders to now being one of the five films receiving the official Oscar nomination nod on Jan. 10. The Academy Awards ceremony will be held on Sunday, Feb. 24, and Bahlman will be watching.

    “I think it has a very good chance of winning,” Bahlman says. “One San Francisco newspaper ranked the top 50 best reviewed films of 2012 and listed How to Survive a Plague as the second best. In comparison, Lincoln ranked 14th and Argo ranked fourth among the list of best reviewed movies by film critics of 2012.”

    Bahlman was a natural leader for both the LGBT movement in the early 1970’s and then again in the 1980’s as the HIV/AIDS movements developed and unfolded.

    “I remember in 1972 leading a group of 10 members of the GAA into a conference of the American Psychiatric Association (APA) at the New York Hilton hotel where they were discussing homosexuality as the disorder they called it,” Bahlman says. “We stood up and declared, ‘how dare you call us disordered and sick.’ They seemed surprised that anyone would be proud to be gay!”

    “Within a year, the APA changed its ruling and no longer called homosexuality a disorder. When you confront people in a peaceful, yet meaningful way, they have to justify their bigotry to your face. In this case, the APA did listen to what we had to say,” Bahlman continues.

    In the mid-1980’s Bahlman returned to direct action with GLAAD.  

    “I look at GLAAD like that parent who doesn’t want to give you permission to try something too extreme,” Bahlman says.

    He remembers organizing actions after the 1986 Supreme Court decision (Bowers v. Hardwick), which upheld a Georgia law criminalizing sodomy.

    “We needed civil disobedience and an opportunity for our people to express their rage,” Bahlman recalls. “We led thousands into the street at Sheridan Square at Christopher Street. We shut down both 7th and 6th Avenues for a few hours and the mayor’s office ordered the NYPD not to arrest us because Mayor Edward Koch recognized and accepted our outrage. This was the first massive LGBT act of civil disobedience in more than a decade.”

    The Lavender Hill Mob was born out of frustration with more mainstream LGBT and AIDS organizations that seemed afraid to empower the communities they represented to perform much needed civil disobedience. A year of highly visible actions by the Lavender Hill Mob followed. A sit-in at a U.S. Senator’s office led to “The Mob” realizing that actions alone were not enough when demanding research to find a cure. 

    “As GAA veterans were the founding members of the Lavender Hill Mob and then ACT UP, ACT UP in a way became a reincarnation of GAA,” Bahlman says. “This type of confrontation politics also has its roots in the American Civil Rights and Women’s Movements.”

    Bahlman and his friends became the earliest lobbyists to dissect the drug approval process and to “follow the money” as to where the research dollars were going. He said they read everything they could get their hands on relating to HIV from the Centers for Disease Control (CDC), the Food & Drug Administration (FDA) and the National Institute’s of Health (NIH).

    “I remember an early meeting with Tony Fauci (MD, Director of the National Institute of Allergy and Infectious Diseases or NIAID) and told him the ACTG semi-annual meetings needed to be open to allow people with AIDS and their advocates to attend,” Bahlman says. “Tony at first hesitated fearing that thousands of people would show up, that he and the other researchers would be overwhelmed, but we made it an ultimatum. Within 24 hours, Tony agreed to formalize our attendance and welcomed us publicly at the opening plenary of the ACTG meeting days later.”

    Twenty-eight years later, Bahlman continues his work with the ACTG and recently completed a term on the Scientific Agenda Steering Committee (SASC) and Executive Committee. He is in the TV studio each week as Associate Producer of Gay USA and awaits the verdict on Feb. 24 for How to Survive a Plague’s Oscar fate.

    “To me the message of the film to today’s audience is that small groups that band together and who believe in what they are doing, can change the world”, Bahlman says. “One must fight injustice, to create a more humane society. The LGBT and people living with HIV/AIDS movements have succeeded from hard work, smart tactics and that we had mercy on our sides.”

  • Co- Infections Explored

    January 1, 1970 pendari Leadership

    Marion Peters, MD, is an internationally renowned hepatologist. She is the John V. Carbone Professor of Medicine at University of California San Francisco and is Chief of Hepatology Research in Gastroenterology. 

    Peters trained in internal medicine, specializing in gastroenterology, hepatology and immunology in Australia, at the University of Southern California and at the National Institutes of Health (NIH). Her research focuses on viral hepatitis; immunology of the liver, including the role of host responses on viral hepatitis; and the effect of alcohol and HIV on liver disease progression.

    She has been a major scientific leader in the AIDS Clinical Trials Group. She has held numerous positions in the ACTG since 1999, including chairing the Liver Diseases Subcommittee and Hepatitis Research Agenda Committee. Peters currently chairs the Hepatitis Transformative Science Group (HEP TSG).  

    “The HEP TSG is comprised of clinicians and scientists from U.S. and international sites with diverse interests and patients,” Peters says. “Our vision is to provide HCV (hepatitis C virus) therapy to all patients living with HCV and HIV co-infection and patients with HCV mono-infection.”  

    She says the group’s goals include:

    1. Devising novel trial designs to accelerate evaluation and approval of new drugs and drug regimens in viral hepatitis.
    2. Expanding and strengthening clinical site capacity to carry out hepatitis trials.
    3. Strengthening capacity to diagnose; monitor; and evaluate clinical, virological and immunological outcomes.
    4. Strengthening hepatitis virologic and pharmacology research capacity for studies of drug-drug interactions between DAAs (direct-acting antivirals), ART (antiretroviral therapy) and other medications.
    5. Mentoring and supporting new investigators to pursue this agenda.

    She was a team member of a major therapeutic study of HIV and HCV co-infection (A5071; New England Journal of Medicine, 2004) and co-chaired the first study comparing adefovir and tenofovir for HIV and hepatitis B virus (HBV) co-infection (A5127; Hepatology 2006; 44: 1110-1116). She was an active contributing protocol team member to A5220 and many sub-analyses of A5071 and A5127. She has continued to contribute to the ACTG through patient referrals and management of HIV and hepatitis co-infected patients. Most recently she is co-chair of study A5269: The Activity of Nitazoxanide in Addition to Pegylated interferon and Ribavirin in Chronic HCV-HIV Co-infected Patients.

  • Meet Michael Lederman, MD

    January 1, 1970 pendari Leadership

    Michael Lederman is the Scott R. Inkley Professor of Medicine at Case Western Reserve University School of Medicine and University Hospitals of Cleveland where he is also Professor of Biomedical Ethics, Pathology, Microbiology and Molecular Biology.

    He received his bachelor’s degree in biology from Brandeis University and his medical degree from the Mt. Sinai School of Medicine. He trained in internal medicine at Case Western Reserve University, University Hospitals of Cleveland and the VA Medical Center where he served as chief resident in medicine and completed fellowship training in infectious diseases. Lederman received post-doctoral training in cellular immunology in the laboratory of Jerrold Ellner, MD, and he joined the faculty at Case in 1980.

    Lederman has been engaged in HIV/AIDS research since he and Oscar Ratnoff, MD, first described and characterized the occurrence of AIDS-related immune deficiency in otherwise healthy men with hemophilia in 1983. He has authored more than 290 peer-reviewed scientific publications largely focused on the mechanisms whereby HIV infection induces immune deficiency and on strategies to correct and prevent it. In 1985, Lederman established the Special Immunology Unit at University Hospitals of Cleveland, which was the first dedicated HIV clinic in Northeast Ohio and is now one of the largest providers of comprehensive HIV care in the Midwestern United States.

    “When the Unit was founded, our doctors felt strongly that the way to assure excellence in HIV care was to link the clinical care program to a strong HIV research program,” Lederman says.

    In 1987, he established the AIDS Clinical Trials Unit at Case/University Hospitals. Within the national network of the AIDS Clinical Trials Group (ACTG), he directs the Immunology Specialty Laboratories that provide immunologic monitoring of national HIV treatment trials. He also leads two program project teams: one that is developing novel topical strategies to prevent HIV acquisition (Basic and Clinical Studies of CCR5 Inhibition to Prevent HIV Transmission) and the other to explore the pathogenesis of immune activation and inflammation in HIV infection (Defining the Pathogenesis of Immune Deficiency in Chronic HIV Infection). He is the chairman of the ACTG’s End-Organ Disease/Inflammation Transformative Science Group.

    “In the HAART (Highly Active Antiretroviral Treatment) era, immune activation and inflammation persist despite virologic control and an increasing body of information links these processes to morbid outcomes,” Lederman says. “Interventional trials provide an important opportunity to preserve the health of our patients and to define the mechanisms that drive activation and inflammation in treated HIV infection.”

    Lederman is a member of the Association of American Physicians, the American Association of Immunologists, the Infectious Diseases Society of America, the HIV Medicine Association and is a Fellow of the American Academy of Microbiology and the American Association for the Advancement of Science. He serves on the editorial boards of several research journals and is a member of the Scientific Advisory Boards for the Forum for Collaborative Research and the Agence Nationale de Recherche sur le SIDA (ANRS).

    Lederman lives with his first wife and two dogs. He owns two daughters and two grandchildren. He swims (slowly) and plays the piano (badly).

  • Meet Savita Kanade of Pune, India

    January 1, 1970 pendari Leadership

    Once a person has participated in a clinical trial at the BJ Medical College AIDS Clinical Trials Group Network’s site in Pune, India, they transition from patient to friend.

    “If we find ourselves in their neighborhood, we will stop in for a visit,” says Savita Kanade, MSc.

    The communication between the clinical trial unit in Pune, about three hours southeast of Mumbai, and its participants is a two way street Kanade has cultivated over the years. Site staff are on the guest list for housewarming parties and weddings. Participants from studies dating as far back as 2007 are among those invited to events held at BJ Medical College, says Kanade, who supervises the Clinical Trial Unit’s outreach program.

    “My goal is to strengthen our CAB (Community Advisory Board) in terms of outreach, recruitment and retention and use social media to achieve this,” she says. “I would also like to develop a website for our CAB.”

    Kanade hails from a strong community health background. Before working at the ACTG site in Pune, she spent 15 years working as a social scientist on projects relating to women’s health including decision-making around abortion, domestic violence, formation of sexual partnership among adolescents and conversations between parents and teens about sex and sexuality.

    In addition to supervising outreach efforts at the Pune site, Kanade serves as CAB liaison and as Co-Vice Chair for the ACTG’s Outreach, Recruitment and Retention (OO&R) Subcommittee.

    “Savita always impresses me with the way she moves through this world,” says Michael Louella, Chair of the OR&R Subcommittee. “Whether it’s embracing new technologies or picking up the check after dinner, she does everything with a quiet grace that to me is sign of true strength and power.”

    She is a familiar face having presented twice at the ACTG Network meeting in Washington, DC, in July 2012. She spoke at the third community session about her CAB and during the OR&R Subcommittee Business Session about a survey she conducted of the Network’s sites and access to communications tools such as the Internet, phones and Fax machines.

    “I want our sites to know how to use social media,” Kanade says. “I post events to the ACTG Facebook page and I want this to be a tool that aids us in recruitment.”

    People living in and around Pune speak mainly Marathi (the local dialect) and Hindi (the national language) or English, and Kanade admits the biggest barrier to informing local people of clinical trial enrollment is translating science into comprehendible terms in the local language. But she is making progress, having translated informed consent materials and protocol schema into Marathi.