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Clinical Infectious Diseases, November 2019 A5288 assessed third-line antiretroviral treatment (ART) in individuals who were failing second-line ART.
Oct 01, 2019
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SCREENING AND ENROLLMENT BY SEX IN HUMAN IMMUNODEFICIENCY VIRUS CLINICAL TRIALS IN THE UNITED STATES
Clinical Infectious Diseases, September 2019 While women represent about one-quarter of adults living with HIV in the United States and over half of people living with HIV worldwide, many HIV clinical trials enroll fewer than 25% women.
Sep 29, 2019
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ACTG DACS 325: SCREENING AND ENROLLMENT BY SEX IN HIV CLINICAL TRIALS IN THE UNITED STATES
Clinical Infectious Diseases, September 2019 While women represent about one-quarter of adults living with HIV in the United States, many HIV clinical trials enroll fewer than 25% women.
Sep 29, 2019
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LINKED DUAL-CLASS HIV RESISTANCE MUTATIONS ASSOCIATED WITH TREATMENT FAILURE
JCI insight, September 2019 Ultrasensitive sequencing of HIV can reveal drug resistance mutations present at very low frequencies, but the clinical significance of those viral resistance mutations remains unknown.
Sep 05, 2019
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The Lancet HIV, September 2019 Tuberculosis (TB) coinfection among pregnant women living with HIV is associated with poor outcomes so effective contraception to prevent unintended pregnancy is of paramount importance for young women with HIV and TB.
Sep 01, 2019
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THE IMPACT OF ART ON THE EFFICACY OF VAGINALLY DELIVERED HORMONAL CONTRACEPTION
The Lancet HIV, September 2019 ACTG Changes Guidelines Effective family planning, which often involves the use of hormonal contraception, is an important component of care for women living with HIV.
Sep 01, 2019
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A LANDMARK ACTG STUDY EVALUATING SECOND-LINE ART FAILURE IN LOW- AND MIDDLE-INCOME COUNTRIES
The Lancet HIV, September 2019 Prolonging the success of ART regimens in light of earlier starts and therapy over a lifetime requires innovative monitoring and treatment strategies.
Sep 01, 2019
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THE IMPACT OF ART ON THE EFFICACY OF VAGINALLY DELIVERED HORMONAL CONTRACEPTION
The Lancet HIV, September 2019 ACTG Changes Guidelines Effective family planning, which often involves the use of hormonal contraception, is an important component of care for women living with HIV.
Sep 01, 2019
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Clinical Infectious Diseases, August 2019 Due to complex interactions between HIV, antiretroviral therapy, and the chronic immune activation and inflammation that can be seen in people living with HIV, there is an increased risk for cardiovascular diseases including acute myocardial infarctions (heart attacks).
Aug 15, 2019
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Journal of Acquired Immune Deficiency Syndrome, August 2019 Although ART suppresses plasma viremia to levels below the level of detection, reservoirs of latently infected cells that lead to viral rebound if ART is stopped persist in people living with HIV.
Aug 15, 2019
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PERSISTENCE OF HIV DNA IN CEREBROSPINAL FLUID AND NEUROLOGICAL IMPLICATIONS
Journal of Clinical Investigation, July 2019 The persistence of HIV in sanctuary sites in the human body even in the presence of antiretroviral therapy (ART) is a potential barrier to HIV remission and cure.
Jul 15, 2019
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OPTIONS STUDY (A5241) ASKS WHETHER NRTIS ARE ESSENTIAL IN SALVAGE REGIMENS
Journal of Infectious Diseases, May 2019 When people with HIV develop resistance to antiretroviral medications, their clinicians often prescribe previously used nucleoside reverse transcriptase inhibitors (NRTIs), along with other drugs, in the new “salvage” regimen, reasoning that the NRTIs may improve the chances of treatment response.
May 28, 2019
