ACTG Publications

TitleAuthorsDateJournalIssueVolume
Use of biological knowledge to inform the analysis of gene-gene interactions involved in modulating virologic failure with efavirenz-containing treatment regimens in ART-naïve ACTG clinical trials participants.Grady, Benjamin J ; Torstenson, Eric S ; McLaren, Paul J ; DE Bakker, Paul I W ; Haas, David W ; Robbins, Gregory K ; Gulick, Roy M ; Haubrich, Richard ; Ribaudo, Heather ; Ritchie, Marylyn D2011Pac Symp Biocomput
Telephone support to improve antiretroviral medication adherence: a multisite, randomized controlled trial.Reynolds, Nancy R ; Testa, Marcia A ; Su, Max ; Chesney, Margaret A ; Neidig, Judith L ; Frank, Ian ; Smith, Scott ; Ickovics, Jeannette ; Robbins, Gregory K ; AIDS Clinical Trials Group 731 and 384 Teams2008 Jan 1J Acquir Immune Defic Syndr147
T cell activation markers and African mitochondrial DNA haplogroups among non-Hispanic black participants in AIDS clinical trials group study 384.Hulgan, Todd ; Robbins, Gregory K ; Kalams, Spyros A ; Samuels, David C ; Grady, Benjamin ; Shafer, Robert ; Murdock, Deborah G ; Selph, Doug ; Haas, David W ; Pollard, Richard B ; AIDS Clinical Trials Group2012PLoS One87
Site nurse-initiated adherence and symptom support telephone calls for HIV-positive individuals starting antiretroviral therapy, ACTG 5031: substudy of ACTG 384.Robbins, Gregory K ; Testa, Marcia A ; Su, Max ; Safren, Steven A ; Morse, Gene ; Lammert, Sara ; Shafer, Robert W ; Reynolds, Nancy R ; Chesney, Margaret A2013 Sep-OctHIV Clin Trials514
Sex differences in the Toll-like receptor-mediated response of plasmacytoid dendritic cells to HIV-1.Meier, Angela ; Chang, J Judy ; Chan, Ellen S ; Pollard, Richard B ; Sidhu, Harlyn K ; Kulkarni, Smita ; Wen, Tom Fang ; Lindsay, Robert J ; Orellana, Liliana ; Mildvan, Donna ; Bazner, Suzane ; Streeck, Hendrik ; Alter, Galit ; Lifson, Jeffrey D ; Carrington, Mary ; Bosch, Ronald J ; Robbins, Gregory K ; Altfeld, Marcus2009 AugNat Med815
Replication capacity in relation to immunologic and virologic outcomes in HIV-1-infected treatment-naive subjects.Skowron, Gail ; Spritzler, John G ; Weidler, Jodi ; Robbins, Gregory K ; Johnson, Victoria A ; Chan, Ellen S ; Asmuth, David M ; Gandhi, Rajesh T ; Lie, Yolanda ; Bates, Michael ; Pollard, Richard B ; NIH/NIAID ACTG 384 Protocol Team and Monogram Biosciences2009 Mar 1J Acquir Immune Defic Syndr350
Racial differences in response to antiretroviral therapy for HIV infection: an AIDS clinical trials group (ACTG) study analysis.Ribaudo, Heather J ; Smith, Kimberly Y ; Robbins, Gregory K ; Flexner, Charles ; Haubrich, Richard ; Chen, Yun ; Fischl, Margaret A ; Schackman, Bruce R ; Riddler, Sharon A ; Gulick, Roy M2013 DecClin Infect Dis1157
Proteinuria, creatinine clearance, and immune activation in antiretroviral-naive HIV-infected subjects.Gupta, Samir K ; Komarow, Lauren ; Gulick, Roy M ; Pollard, Richard B ; Robbins, Gregory K ; Franceschini, Nora ; Szczech, Lynda A ; Koletar, Susan L ; Kalayjian, Robert C2009 Aug 15J Infect Dis4200
Pretreatment levels of soluble cellular receptors and interleukin-6 are associated with HIV disease progression in subjects treated with highly active antiretroviral therapy.Kalayjian, Robert C ; Machekano, Rhoderick N ; Rizk, Nesrine ; Robbins, Gregory K ; Gandhi, Rajesh T ; Rodriguez, Benigno A ; Pollard, Richard B ; Lederman, Michael M ; Landay, Alan2010 Jun 15J Infect Dis12201
Predictors of antiretroviral-related hepatotoxicity in the adult AIDS Clinical Trial Group (1989-1999).Servoss, Julie C ; Kitch, Douglas W ; Andersen, Janet W ; Reisler, Ronald B ; Chung, Raymond T ; Robbins, Gregory K2006 Nov 1J Acquir Immune Defic Syndr343
Phenome-wide Association Study Relating Pretreatment Laboratory Parameters With Human Genetic Variants in AIDS Clinical Trials Group Protocols.Moore, Carrie B ; Verma, Anurag ; Pendergrass, Sarah ; Verma, Shefali S ; Johnson, Daniel H ; Daar, Eric S ; Gulick, Roy M ; Haubrich, Richard ; Robbins, Gregory K ; Ritchie, Marylyn D ; Haas, David W2015 JanOpen Forum Infect Dis12
Partner-Focused Adherence Intervention for Second-line Antiretroviral Therapy: A Multinational Randomized Trial (ACTG A5234).Gross, Robert ; Zheng, Lu ; La Rosa, Alberto ; Sun, Xin ; Rosenkranz, Susan L ; Cardoso, Sandra Wagner ; Ssali, Francis ; Camp, Rob ; Godfrey, Catherine ; Cohn, Susan E ; Robbins, Gregory K ; Chisada, Anthony ; Wallis, Carole L ; Reynolds, Nancy R ; Lu, Darlene ; Safren, Steven A ; Hosey, Lara ; Severe, Patrice ; Collier, Ann C2015 Jan 1Lancet HIV12
Oxidant stress and peripheral neuropathy during antiretroviral therapy: an AIDS clinical trials group study.Hulgan, Todd ; Hughes, Michael ; Sun, Xin ; Smeaton, Laura M ; Terry, Erin ; Robbins, Gregory K ; Shafer, Robert W ; Clifford, David B ; McComsey, Grace A ; Canter, Jeffery A ; Morrow, Jason D ; Haas, David W2006 Aug 1J Acquir Immune Defic Syndr442
Multilocus genetic interactions and response to efavirenz-containing regimens: an adult AIDS clinical trials group study.Motsinger, Alison A ; Ritchie, Marylyn D ; Shafer, Robert W ; Robbins, Gregory K ; Morse, Gene D ; Labbe, Line ; Wilkinson, Grant R ; Clifford, David B ; D'Aquila, Richard T ; Johnson, Victoria A ; Pollard, Richard B ; Merigan, Thomas C ; Hirsch, Martin S ; Donahue, John P ; Kim, Richard B ; Haas, David W2006 NovPharmacogenet Genomics1116
Mixed patterns of changes in central and peripheral fat following initiation of antiretroviral therapy in a randomized trial.Mulligan, Kathleen ; Parker, Robert A ; Komarow, Lauren ; Grinspoon, Steven K ; Tebas, Pablo ; Robbins, Gregory K ; Roubenoff, Ronenn ; Dubé, Michael P2006 Apr 15J Acquir Immune Defic Syndr541
Mitochondrial genomics and CD4 T-cell count recovery after antiretroviral therapy initiation in AIDS clinical trials group study 384.Grady, Benjamin J ; Samuels, David C ; Robbins, Gregory K ; Selph, Doug ; Canter, Jeffrey A ; Pollard, Richard B ; Haas, David W ; Shafer, Robert ; Kalams, Spyros A ; Murdock, Deborah G ; Ritchie, Marylyn D ; Hulgan, Todd ; ACTG 384 and DACS 250 Study Teams2011 Dec 1J Acquir Immune Defic Syndr458
Measurement of naive CD4 cells reliably predicts potential for immune reconstitution in HIV.Schacker, Timothy W ; Bosch, Ronald J ; Bennett, Kara ; Pollard, Richard ; Robbins, Gregory K ; Collier, Ann C ; Gulick, Roy M ; Spritzler, John ; Mildvan, Donna ; AIDS Clinical Trials Group2010 May 1J Acquir Immune Defic Syndr154
The major genetic determinants of HIV-1 control affect HLA class I peptide presentation.International HIV Controllers Study ; Pereyra, Florencia ; Jia, Xiaoming ; McLaren, Paul J ; Telenti, Amalio ; DE Bakker, Paul I W ; Walker, Bruce D ; Ripke, Stephan ; Brumme, Chanson J ; Pulit, Sara L ; Carrington, Mary ; Kadie, Carl M ; Carlson, Jonathan M ; Heckerman, David ; Graham, Robert R ; Plenge, Robert M ; Deeks, Steven G ; Giann2010 Dec 10Science6010330
Long-term increase in CD4+ T-cell counts during combination antiretroviral therapy for HIV-1 infection.Lok, Judith J ; Bosch, Ronald J ; Benson, Constance A ; Collier, Ann C ; Robbins, Gregory K ; Shafer, Robert W ; Hughes, Michael D ; ALLRT team2010 Jul 31AIDS1224
Long-term body fat outcomes in antiretroviral-naive participants randomized to nelfinavir or efavirenz or both plus dual nucleosides. Dual X-ray absorptiometry results from A5005s, a substudy of Adult Clinical Trials Group 384.Dubé, Michael P ; Komarow, Lauren ; Mulligan, Kathleen ; Grinspoon, Steven K ; Parker, Robert A ; Robbins, Gregory K ; Roubenoff, Ronenn ; Tebas, Pablo ; Adult Clinical Trials Group 3842007 Aug 15J Acquir Immune Defic Syndr545
Incomplete reconstitution of T cell subsets on combination antiretroviral therapy in the AIDS Clinical Trials Group protocol 384.Robbins, Gregory K ; Spritzler, John G ; Chan, Ellen S ; Asmuth, David M ; Gandhi, Rajesh T ; Rodriguez, Benigno A ; Skowron, Gail ; Skolnik, Paul R ; Shafer, Robert W ; Pollard, Richard B ; AIDS Clinical Trials Group 384 Team2009 Feb 1Clin Infect Dis348
Higher expression of several interferon-stimulated genes in HIV-1-infected females after adjusting for the level of viral replication.Chang, J Judy ; Woods, Matt ; Lindsay, Robert J ; Doyle, Erin H ; Griesbeck, Morgane ; Chan, Ellen S ; Robbins, Gregory K ; Bosch, Ronald J ; Altfeld, Marcus2013 Sep 1J Infect Dis5208
Hemochromatosis (HFE) gene mutations and peripheral neuropathy during antiretroviral therapy.Kallianpur, Asha R ; Hulgan, Todd ; Canter, Jeffrey A ; Ritchie, Marylyn D ; Haines, Jonathan L ; Robbins, Gregory K ; Shafer, Robert W ; Clifford, David B ; Haas, David W2006 Jul 13AIDS1120
Hemochromatosis gene polymorphisms, mitochondrial haplogroups, and peripheral lipoatrophy during antiretroviral therapy.Hulgan, Todd ; Tebas, Pablo ; Canter, Jeffrey A ; Mulligan, Kathleen ; Haas, David W ; Dubé, Michael ; Grinspoon, Steven ; Robbins, Gregory K ; Motsinger, Alison A ; Kallianpur, Asha R ; AIDS Clinical Trials Group 384 and A5005s Study Teams2008 Mar 15J Infect Dis6197
Hematologic toxicity associated with interferon-based hepatitis C therapy in HIV type 1-coinfected subjects.Behler, Caroline M ; Vittinghoff, Eric ; Lin, Feng ; Chung, Raymond T ; Peters, Marion G ; Robbins, Gregory K ; Volberding, Paul A2007 May 15Clin Infect Dis1044
Genome-wide association study of virologic response with efavirenz-containing or abacavir-containing regimens in AIDS clinical trials group protocols.Lehmann, David S ; Ribaudo, Heather J ; Daar, Eric S ; Gulick, Roy M ; Haubrich, Richard H ; Robbins, Gregory K ; DE Bakker, Paul I W ; Haas, David W ; McLaren, Paul J2015 FebPharmacogenet Genomics225
Genome-wide association study of plasma efavirenz pharmacokinetics in AIDS Clinical Trials Group protocols implicates several CYP2B6 variants.Holzinger, Emily R ; Grady, Benjamin ; Ritchie, Marylyn D ; Ribaudo, Heather J ; Acosta, Edward P ; Morse, Gene D ; Gulick, Roy M ; Robbins, Gregory K ; Clifford, David B ; Daar, Eric S ; McLaren, Paul ; Haas, David W2012 DecPharmacogenet Genomics1222
Genome-wide association study of peripheral neuropathy with D-drug-containing regimens in AIDS Clinical Trials Group protocol 384.Leger, Paul D ; Johnson, Daniel H ; Robbins, Gregory K ; Shafer, Robert W ; Clifford, David B ; Li, Jun ; McLaren, Paul J ; Haas, David W2014 JunJ Neurovirol320
GB virus C (GBV-C) infection in hepatitis C virus (HCV)/HIV-coinfected patients receiving HCV treatment: importance of the GBV-C genotype.Schwarze-Zander, Carolynne ; Blackard, Jason T ; Zheng, Hui ; Addo, Marylyn M ; Lin, Wenyu ; Robbins, Gregory K ; Sherman, Kenneth E ; Zdunek, Dietmar ; Hess, Georg ; Chung, Raymond T ; AIDS Clinical Trial Group A5071 Study Team2006 Aug 15J Infect Dis4194
Effects of potent antiretroviral therapy on free testosterone levels and fat-free mass in men in a prospective, randomized trial: A5005s, a substudy of AIDS Clinical Trials Group Study 384.Dubé, Michael P ; Parker, Robert A ; Mulligan, Kathleen ; Tebas, Pablo ; Robbins, Gregory K ; Roubenoff, Ronenn ; Grinspoon, Steven K2007 Jul 1Clin Infect Dis145
Effect of CYP2B6, ABCB1, and CYP3A5 polymorphisms on efavirenz pharmacokinetics and treatment response: an AIDS Clinical Trials Group study.Ribaudo, Heather J ; Liu, Huan ; Schwab, Matthias ; Schaeffeler, Elke ; Eichelbaum, Michel ; Motsinger-Reif, Alison A ; Ritchie, Marylyn D ; Zanger, Ulrich M ; Acosta, Edward P ; Morse, Gene D ; Gulick, Roy M ; Robbins, Gregory K ; Clifford, David ; Haas, David W2010 Sep 1J Infect Dis5202
Effect of baseline- and treatment-related factors on immunologic recovery after initiation of antiretroviral therapy in HIV-1-positive subjects: results from ACTG 384.Gandhi, Rajesh T ; Spritzler, John ; Chan, Ellen ; Asmuth, David M ; Rodriguez, Benigno ; Merigan, Thomas C ; Hirsch, Martin S ; Shafer, Robert W ; Robbins, Gregory K ; Pollard, Richard B ; ACTG 384 Team2006 Aug 1J Acquir Immune Defic Syndr442
Dynamics of total, linear nonintegrated, and integrated HIV-1 DNA in vivo and in vitro.Koelsch, Kersten K ; Liu, Lin ; Haubrich, Richard ; May, Susanne ; Havlir, Diane ; Günthard, Huldrych F ; Ignacio, Caroline C ; Campos-Soto, Paula ; Little, Susan J ; Shafer, Robert ; Robbins, Gregory K ; D'Aquila, Richard T ; Kawano, Yuji ; Young, Karen ; Dao, Phillip ; Spina, Celsa A ; Richman, Douglas D ; Wong, Joseph K2008 Feb 1J Infect Dis3197
Characteristics associated with virologic failure in high-risk HIV-positive participants with prior failure: a post hoc analysis of ACTG 5251.Robbins, Gregory K ; Cohn, Susan E ; Harrison, Linda J ; Smeaton, Laura ; Moran, Laura ; Rusin, David ; Dehlinger, Marjorie ; Flynn, Theresa ; Lammert, Sara ; Wu, Albert W ; Safren, Steven A ; Reynolds, Nancy R2016 JulHIV Clin Trials417
African mitochondrial DNA subhaplogroups and peripheral neuropathy during antiretroviral therapy.Canter, Jeffrey A ; Robbins, Gregory K ; Selph, Doug ; Clifford, David B ; Kallianpur, Asha R ; Shafer, Robert ; Levy, Shawn ; Murdock, Deborah G ; Ritchie, Marylyn D ; Haas, David W ; Hulgan, Todd ; AIDS Clinical Trials Group Study 384 Team ; New Work Concept Sheet 273 Team2010 Jun 1J Infect Dis11201