ACTG Publications

TitleAuthorsDateJournalIssueVolume
Safety and antiviral activity of the HCV entry inhibitor ITX5061 in treatment-naive HCV-infected adults: a randomized, double-blind, phase 1b study.Sulkowski, Mark S ; Kang, Minhee ; Matining, Roy ; Wyles, David ; Johnson, Victoria A ; Morse, Gene D ; Amorosa, Valerianna ; Bhattacharya, Debika ; Coughlin, Kristine ; Wong-Staal, Flossie ; Glesby, Marshall J ; AIDS Clinical Trials Group A5277 Protocol Team2014 Mar 1J Infect Dis5209
Safety and efficacy of extended-release niacin for the treatment of dyslipidaemia in patients with HIV infection: AIDS Clinical Trials Group Study A5148.Dubé, Michael P ; Wu, Julia W ; Aberg, Judith A ; Deeg, Mark A ; Alston-Smith, Beverly L ; McGovern, Mark E ; Lee, Daniel ; Shriver, Sharon L ; Martinez, Ana I ; Greenwald, Martha ; Stein, James H ; AIDS Clinical Trials Group A5148 Study Team2006Antivir Ther811
The Safety and Immunogenicity of an Interleukin-12-Enhanced Multiantigen DNA Vaccine Delivered by Electroporation for the Treatment of HIV-1 Infection.Jacobson, Jeffrey M ; Zheng, Lu ; Wilson, Cara C ; Tebas, Pablo ; Matining, Roy M ; Egan, Michael A ; Eldridge, John ; Landay, Alan L ; Clifford, David B ; Luetkemeyer, Anne F ; Tiu, Jennifer ; Martinez, Ana L ; Janik, Jennifer ; Spitz, Teresa A ; Hural, John ; McElrath, Juliana ; Frahm, Nicole ; ACTG A5281 Protocol Team2016 Feb 1J Acquir Immune Defic Syndr271
Safety and immunogenicity of the quadrivalent human papillomavirus vaccine in HIV-1-infected men.Wilkin, Timothy ; Lee, Jeannette Y ; Lensing, Shelly Y ; Stier, Elizabeth A ; Goldstone, Stephen E ; Berry, J Michael ; Jay, Naomi ; Aboulafia, David ; Cohn, David L ; Einstein, Mark H ; Saah, Alfred ; Mitsuyasu, Ronald T ; Palefsky, Joel M2010 Oct 15J Infect Dis8202
Safety and immunogenicity of therapeutic DNA vaccination in individuals treated with antiretroviral therapy during acute/early HIV-1 infection.Rosenberg, Eric S ; Graham, Barney S ; Chan, Ellen S ; Bosch, Ronald J ; Stocker, Vicki ; Maenza, Janine ; Markowitz, Martin ; Little, Susan ; Sax, Paul E ; Collier, Ann C ; Nabel, Gary ; Saindon, Suzanne ; Flynn, Theresa ; Kuritzkes, Daniel ; Barouch, Dan H ; AIDS Clinical Trials Group A5187 Team2010PLoS One55
Safety and tolerability of depot medroxyprogesterone acetate among HIV-infected women on antiretroviral therapy: ACTG A5093.Watts, D Heather ; Park, Jeong-Gun ; Cohn, Susan E ; Yu, Song ; Hitti, Jane ; Stek, Alice ; Clax, Pamela A ; Muderspach, Laila ; Lertora, Juan J L2008 FebContraception277
Safety and Tolerability of Maraviroc-Containing Regimens to Prevent HIV Infection in Women: A Phase 2 Randomized Trial.Gulick, Roy M ; Wilkin, Timothy J ; Chen, Ying Q ; Landovitz, Raphael J ; Amico, K Rivet ; Young, Alicia M ; Richardson, Paul ; Marzinke, Mark A ; Hendrix, Craig W ; Eshleman, Susan H ; McGowan, Ian ; Cottle, Leslie M ; Andrade, Adriana ; Marcus, Cheryl ; Klingman, Karin L ; Chege, Wairimu ; Rinehart, Alex R ; Rooney, James F ; Andrew, Phi2017 Sep 19Ann Intern Med6167
Safety, tolerability, and immunogenicity of repeated doses of dermavir, a candidate therapeutic HIV vaccine, in HIV-infected patients receiving combination antiretroviral therapy: results of the ACTG 5176 trial.Rodriguez, Benigno ; Asmuth, David M ; Matining, Roy M ; Spritzler, John ; Jacobson, Jeffrey M ; Mailliard, Robbie B ; Li, Xiao-Dong ; Martinez, Ana I ; Tenorio, Allan R ; Lori, Franco ; Lisziewicz, Julianna ; Yesmin, Suria ; Rinaldo, Charles R ; Pollard, Richard B2013 Dec 1J Acquir Immune Defic Syndr464
Safety, tolerability, and mechanisms of antiretroviral activity of pegylated interferon Alfa-2a in HIV-1-monoinfected participants: a phase II clinical trial.Asmuth, David M ; Murphy, Robert L ; Rosenkranz, Susan L ; Lertora, Juan J L ; Kottilil, Shyam ; Cramer, Yoninah ; Chan, Ellen S ; Schooley, Robert T ; Rinaldo, Charles R ; Thielman, Nathan ; Li, Xiao-Dong ; Wahl, Sharon M ; Shore, Jessica ; Janik, Jennifer ; Lempicki, Richard A ; Simpson, Yaa ; Pollard, Richard B ; AIDS Clinical Trials Gr2010 Jun 1J Infect Dis11201
Safety, tolerability, and pharmacokinetic interactions of the antituberculous agent TMC207 (bedaquiline) with efavirenz in healthy volunteers: AIDS Clinical Trials Group Study A5267.Dooley, Kelly E ; Park, Jeong-Gun ; Swindells, Susan ; Allen, Reena ; Haas, David W ; Cramer, Yoninah ; Aweeka, Francesca ; Wiggins, Ilene ; Gupta, Amita ; Lizak, Patricia ; Qasba, Sonia ; van Heeswijk, Rolf ; Flexner, Charles ; ACTG 5267 Study Team2012 Apr 15J Acquir Immune Defic Syndr559
Safety, tolerability, pharmacokinetics, and efficacy of an interleukin-2 agonist among HIV-infected patients receiving highly active antiretroviral therapy.Davey, Richard T ; Pertel, Peter E ; Benson, Alice ; Cassell, Delanie J ; Gazzard, Brian G ; Holodniy, Mark ; Lalezari, Jacob P ; Levy, Yves ; Mitsuyasu, Ronald T ; Palella, Frank J ; Pollard, Richard B ; Rajagopalan, Prabhu ; Saag, Michael S ; Salata, Robert A ; Sha, Beverly E ; Choudhri, Shurjeel2008 FebJ Interferon Cytokine Res228
Screening for pulmonary tuberculosis in HIV-infected individuals: AIDS Clinical Trials Group Protocol A5253.Swindells, S ; Komarow, L ; Tripathy, S ; Cain, K P ; MacGregor, R R ; Achkar, J M ; Gupta, A ; Veloso, V G ; Asmelash, A ; Omoz-Oarhe, A E ; Gengiah, S ; Lalloo, U ; Allen, R ; Shiboski, C ; Andersen, J ; Qasba, S S ; Katzenstein, D K ; AIDS Clinical Trials Group 5253 Study Team2013 AprInt J Tuberc Lung Dis417
Screening for UGT1A1 Genotype in Study A5257 Would Have Markedly Reduced Premature Discontinuation of Atazanavir for Hyperbilirubinemia.Vardhanabhuti, Saran ; Ribaudo, Heather J ; Landovitz, Raphael J ; Ofotokun, Ighovwerha ; Lennox, Jeffrey L ; Currier, Judith S ; Olson, Lana M ; Haas, David W2015 SepOpen Forum Infect Dis32
Second assessment of NeuroAIDS in Africa.Robertson, Kevin ; Kopnisky, Kathy ; Hakim, James ; Merry, Concepta ; Nakasujja, Noeline ; Hall, Colin ; Traore, Moussa ; Sacktor, Ned ; Clifford, David ; Newton, Charles ; Van Rie, Annelies ; Holding, Penny ; Clements, Janice ; Zink, Christine ; Mielk, Jens ; Hosseinipour, Mina ; Lalloo, Umesh ; Amod, Farida ; Marra, Christina ; Evans, Sc2008 AprJ Neurovirol214
Secondary metabolism pathway polymorphisms and plasma efavirenz concentrations in HIV-infected adults with CYP2B6 slow metabolizer genotypes.Haas, David W ; Kwara, Awewura ; Richardson, Danielle M ; Baker, Paxton ; Papageorgiou, Ioannis ; Acosta, Edward P ; Morse, Gene D ; Court, Michael H2014 AugJ Antimicrob Chemother869
Selection and persistence of non-nucleoside reverse transcriptase inhibitor-resistant HIV-1 in patients starting and stopping non-nucleoside therapy.Palmer, Sarah ; Boltz, Valerie ; Maldarelli, Frank ; Kearney, Mary ; Halvas, Elias K ; Rock, Diane ; Falloon, Judith ; Davey, Richard T ; Dewar, Robin L ; Metcalf, Julia A ; Mellors, John W ; Coffin, John M2006 Mar 21AIDS520
Selective Loss of Early Differentiated, Highly Functional PD1high CD4 T Cells with HIV Progression.Paris, Robert M ; Petrovas, Constantinos ; Ferrando-Martinez, Sara ; Moysi, Eirini ; Boswell, Kristin L ; Archer, Eva ; Yamamoto, Takuya ; Ambrozak, David ; Casazza, Joseph P ; Haubrich, Richard ; Connors, Mark ; Ake, Julie ; Kim, Jerome H ; Koup, Richard A2015PLoS One1210
Selegiline and oxidative stress in HIV-associated cognitive impairment.Schifitto, G ; Yiannoutsos, C T ; Ernst, T ; Navia, B A ; Nath, A ; Sacktor, N ; Anderson, C ; Marra, C M ; Clifford, D B ; ACTG 5114 Team2009 Dec 8Neurology2373
Selegiline transdermal system (STS) for HIV-associated cognitive impairment: open-label report of ACTG 5090.Evans, Scott R ; Yeh, Tzu-min ; Sacktor, Ned ; Clifford, David B ; Simpson, David ; Miller, Eric N ; Ellis, Ronald J ; Valcour, Victor ; Marra, Christina M ; Millar, Linda ; Schifitto, Giovanni ; AIDS Clinical Trials Group and the Neurologic AIDS Research Consortium2007 Nov-DecHIV Clin Trials68
Sensitive assay for determining plasma tenofovir concentrations by LC/MS/MS.Delahunty, Tom ; Bushman, Lane ; Fletcher, Courtney V2006 Jan 2J Chromatogr B Analyt Technol Biomed Life Sci1830
Serosorting can potentially increase HIV transmissions.Butler, David M ; Smith, Davey M2007 May 31AIDS921
The setpoint study (ACTG A5217): effect of immediate versus deferred antiretroviral therapy on virologic set point in recently HIV-1-infected individuals.Hogan, Christine M ; Degruttola, Victor ; Sun, Xin ; Fiscus, Susan A ; Del Rio, Carlos ; Hare, C Bradley ; Markowitz, Martin ; Connick, Elizabeth ; Macatangay, Bernard ; Tashima, Karen T ; Kallungal, Beatrice ; Camp, Rob ; Morton, Tia ; Daar, Eric S ; Little, Susan ; A5217 Study Team2012 Jan 1J Infect Dis1205
Sevelamer does not decrease lipopolysaccharide or soluble CD14 levels but decreases soluble tissue factor, low-density lipoprotein (LDL) cholesterol, and oxidized LDL cholesterol levels in individuals with untreated HIV infection.Sandler, Netanya G ; Zhang, Xinyan ; Bosch, Ronald J ; Funderburg, Nicholas T ; Choi, Andrew I ; Robinson, Janet K ; Fine, Derek M ; Coombs, Robert W ; Jacobson, Jeffrey M ; Landay, Alan L ; Douek, Daniel C ; Tressler, Randall ; Read, Sarah W ; Wilson, Cara C ; Deeks, Steven G ; Lederman, Michael M ; Gandhi, Rajesh T ; AIDS Clinical Trials2014 Nov 15J Infect Dis10210
Sex differences in atazanavir pharmacokinetics and associations with time to clinical events: AIDS Clinical Trials Group Study A5202.Venuto, Charles S ; Mollan, Katie ; Ma, Qing ; Daar, Eric S ; Sax, Paul E ; Fischl, Margaret ; Collier, Ann C ; Smith, Kimberly Y ; Tierney, Camlin ; Morse, Gene D2014 DecJ Antimicrob Chemother1269
Sex differences in lopinavir and ritonavir pharmacokinetics among HIV-infected women and men.Umeh, Obi C ; Currier, Judith S ; Park, Jeong-Gun ; Cramer, Yoninah ; Hermes, Ashwaq E ; Fletcher, Courtney V2011 DecJ Clin Pharmacol1251
Sex differences in the Toll-like receptor-mediated response of plasmacytoid dendritic cells to HIV-1.Meier, Angela ; Chang, J Judy ; Chan, Ellen S ; Pollard, Richard B ; Sidhu, Harlyn K ; Kulkarni, Smita ; Wen, Tom Fang ; Lindsay, Robert J ; Orellana, Liliana ; Mildvan, Donna ; Bazner, Suzane ; Streeck, Hendrik ; Alter, Galit ; Lifson, Jeffrey D ; Carrington, Mary ; Bosch, Ronald J ; Robbins, Gregory K ; Altfeld, Marcus2009 AugNat Med815
Sex-associated differences in pre-antiretroviral therapy plasma HIV-1 RNA in diverse areas of the world vary by CD4(+) T-cell count.Grinsztejn, Beatriz ; Smeaton, Laura ; Barnett, Ronald ; Klingman, Karin ; Hakim, James ; Flanigan, Timothy ; Kumarasamy, N ; Campbell, Thomas ; Currier, Judith ; PEARLS study team of the ACTG2011Antivir Ther716
Sex-related Differences in Inflammatory and Immune Activation Markers before and after combined Antiretroviral Therapy Initiation.Mathad, Jyoti S ; Gupte, Nikhil ; Balagopal, Ashwin ; Asmuth, David ; Hakim, James ; Santos, Breno ; Riviere, Cynthia ; Hosseinipour, Mina ; Sugandhavesa, Patcharaphan ; Infante, Rosa ; Pillay, Sandy ; Cardoso, Sandra W ; Mwelase, Noluthando ; Pawar, Jyoti ; Berendes, Sima ; Kumarasamy, Nagalingeswaran ; Andrade, Bruno B ; Campbell, Thomas2016 May 27J Acquir Immune Defic Syndr
Short-term ezetimibe is well tolerated and effective in combination with statin therapy to treat elevated LDL cholesterol in HIV-infected patients.Chow, Dominic ; Chen, Huichao ; Glesby, Marshall J ; Busti, Anthony ; Souza, Scott ; Andersen, Janet ; Kohrs, Sharon ; Wu, Julia ; Koletar, Susan L2009 Oct 23AIDS1623
Simian immunodeficiency virus engrafted with human immunodeficiency virus type 1 (HIV-1)-specific epitopes: replication, neutralization, and survey of HIV-1-positive plasma.Yuste, Eloisa ; Sanford, Hannah B ; Carmody, Jill ; Bixby, Jacqueline ; Little, Susan ; Zwick, Michael B ; Greenough, Tom ; Burton, Dennis R ; Richman, Douglas D ; Desrosiers, Ronald C ; Johnson, Welkin E2006 MarJ Virol680
Simplification of the research diagnosis of HIV-associated sensory neuropathy.Evans, Scott R ; Clifford, David B ; Kitch, Douglas W ; Goodkin, Karl ; Schifitto, Giovanni ; McArthur, Justin C ; Simpson, David M2008 Nov-DecHIV Clin Trials69
Site nurse-initiated adherence and symptom support telephone calls for HIV-positive individuals starting antiretroviral therapy, ACTG 5031: substudy of ACTG 384.Robbins, Gregory K ; Testa, Marcia A ; Su, Max ; Safren, Steven A ; Morse, Gene ; Lammert, Sara ; Shafer, Robert W ; Reynolds, Nancy R ; Chesney, Margaret A2013 Sep-OctHIV Clin Trials514
The size of the expressed HIV reservoir predicts timing of viral rebound after treatment interruption.Li, Jonathan Z ; Etemad, Behzad ; Ahmed, Hayat ; Aga, Evgenia ; Bosch, Ronald J ; Mellors, John W ; Kuritzkes, Daniel R ; Lederman, Michael M ; Para, Michael ; Gandhi, Rajesh T2016 Jan 28AIDS330
Sofosbuvir Plus Ribavirin Without Interferon for Treatment of Acute Hepatitis C Virus Infection in HIV-1-Infected Individuals: SWIFT-C.Naggie, Susanna ; Marks, Kristen M ; Hughes, Michael ; Fierer, Daniel S ; Macbrayne, Christine ; Kim, Arthur ; Hollabaugh, Kimberly ; Roa, Jhoanna ; Symonds, Bill ; Brainard, Diana M ; McHutchison, John G ; Peters, Marion G ; Kiser, Jennifer J ; Chung, Raymond ; AIDS Clinical Trials Group (ACTG) A5327 Study Team2017 04 15Clin Infect Dis864
Soluble Levels of Receptor for Advanced Glycation Endproducts (RAGE) and Progression of Atherosclerosis in Individuals Infected with Human Immunodeficiency Virus: ACTG NWCS 332.Danoff, Ann ; Kendall, Michelle A ; Currier, Judith S ; Kelesidis, Theodoros ; Schmidt, Ann Marie ; Aberg, Judith A2016 AugInflammation439
Soluble markers of inflammation and coagulation but not T-cell activation predict non-AIDS-defining morbid events during suppressive antiretroviral treatment.Tenorio, Allan R ; Zheng, Yu ; Bosch, Ronald J ; Krishnan, Supriya ; Rodriguez, Benigno ; Hunt, Peter W ; Plants, Jill ; Seth, Arjun ; Wilson, Cara C ; Deeks, Steven G ; Lederman, Michael M ; Landay, Alan L2014 Oct 15J Infect Dis8210
S-phase entry leads to cell death in circulating T cells from HIV-infected persons.Sieg, Scott F ; Bazdar, Douglas A ; Lederman, Michael M2008 JunJ Leukoc Biol683
Statin therapy and changes in hip circumference among HIV-infected participants in the ALLRT Cohort.Brown, Todd T ; Smurzynski, Marlene ; Wu, Kunling ; Bosch, Ronald J ; McComsey, Grace A2009Antivir Ther614
Statistical determination of threshold for cellular division in the CFSE-labeling assay.Liu, Dacheng ; Yu, Jie ; Chen, Huiyuan ; Reichman, Richard ; Wu, Hulin ; Jin, Xia2006 May 30J Immunol Methods1-2312
A statistical framework for quantile equivalence clinical trials with application to pharmacokinetic studies that bridge from HIV-infected adults to children.Pei, Lixia ; Hughes, Michael D2008 DecBiometrics464
Substitution of nevirapine because of efavirenz toxicity in AIDS clinical trials group A5095.Schouten, Jeffrey T ; Krambrink, Amy ; Ribaudo, Heather J ; Kmack, Anne ; Webb, Nancy ; Shikuma, Cecilia ; Kuritzkes, Daniel R ; Gulick, Roy M2010 Mar 1Clin Infect Dis550
Suppression of HIV-1 replication by antiretroviral therapy improves renal function in persons with low CD4 cell counts and chronic kidney disease.Kalayjian, Robert C ; Franceschini, Nora ; Gupta, Samir K ; Szczech, Lynda A ; Mupere, Ezekiel ; Bosch, Ronald J ; Smurzynski, Marlene ; Albert, Jeffrey M2008 Feb 19AIDS422
Surface expression patterns of negative regulatory molecules identify determinants of virus-specific CD8+ T-cell exhaustion in HIV infection.Yamamoto, Takuya ; Price, David A ; Casazza, Joseph P ; Ferrari, Guido ; Nason, Martha ; Chattopadhyay, Pratip K ; Roederer, Mario ; Gostick, Emma ; Katsikis, Peter D ; Douek, Daniel C ; Haubrich, Richard ; Petrovas, Constantinos ; Koup, Richard A2011 May 5Blood18117
A survey of tuberculosis infection control practices at the NIH/NIAID/DAIDS-supported clinical trial sites in low and middle income countries.Godfrey, Catherine ; Tauscher, Gail ; Hunsberger, Sally ; Austin, Melissa ; Scott, Lesley ; Schouten, Jeffrey T ; Luetkemeyer, Anne F ; Benson, Constance ; Coombs, Robert ; Swindells, Susan ; HIV Network Coordinating (HANC) TB Diagnostic Laboratory Working Division of AIDS, National Institute of Allergy and Infectious Diseases2016 06 10BMC Infect Dis16
Sustained long-term antiviral maintenance therapy in HCV/HIV-coinfected patients (SLAM-C).Sherman, Kenneth E ; Andersen, Janet W ; Butt, Adeel A ; Umbleja, Triin ; Alston, Beverly ; Koziel, Margaret J ; Peters, Marion G ; Sulkowski, Mark ; Goodman, Zachary D ; Chung, Raymond T ; AIDS Clinical Trials Group A5178 Study Team2010 Dec 15J Acquir Immune Defic Syndr555
Switching to a protease inhibitor-containing, nucleoside-sparing regimen (lopinavir/ritonavir plus efavirenz) increases limb fat but raises serum lipid levels: results of a prospective randomized trial (AIDS clinical trial group 5125s).Tebas, Pablo ; Zhang, Jiameng ; Yarasheski, Kevin ; Evans, Scott ; Fischl, Margaret A ; Shevitz, Abby ; Feinberg, Judith ; Collier, Ann C ; Shikuma, Cecilia ; Brizz, Barbara ; Sattler, Fred ; AIDS Clinical Trials Group (ACTG)2007 Jun 1J Acquir Immune Defic Syndr245