ACTG Publications

TitleAuthorsDateJournalIssueVolume
Safety and antiviral activity of the HCV entry inhibitor ITX5061 in treatment-naive HCV-infected adults: a randomized, double-blind, phase 1b study.Sulkowski, Mark S ; Kang, Minhee ; Matining, Roy ; Wyles, David ; Johnson, Victoria A ; Morse, Gene D ; Amorosa, Valerianna ; Bhattacharya, Debika ; Coughlin, Kristine ; Wong-Staal, Flossie ; Glesby, Marshall J ; AIDS Clinical Trials Group A5277 Protocol Team2014 Mar 1J Infect Dis5209
Safety and efficacy of extended-release niacin for the treatment of dyslipidaemia in patients with HIV infection: AIDS Clinical Trials Group Study A5148.Dubé, Michael P ; Wu, Julia W ; Aberg, Judith A ; Deeg, Mark A ; Alston-Smith, Beverly L ; McGovern, Mark E ; Lee, Daniel ; Shriver, Sharon L ; Martinez, Ana I ; Greenwald, Martha ; Stein, James H ; AIDS Clinical Trials Group A5148 Study Team2006Antivir Ther811
The Safety and Immunogenicity of an Interleukin-12-Enhanced Multiantigen DNA Vaccine Delivered by Electroporation for the Treatment of HIV-1 Infection.Jacobson, Jeffrey M ; Zheng, Lu ; Wilson, Cara C ; Tebas, Pablo ; Matining, Roy M ; Egan, Michael A ; Eldridge, John ; Landay, Alan L ; Clifford, David B ; Luetkemeyer, Anne F ; Tiu, Jennifer ; Martinez, Ana L ; Janik, Jennifer ; Spitz, Teresa A ; Hural, John ; McElrath, Juliana ; Frahm, Nicole ; ACTG A5281 Protocol Team2016 Feb 1J Acquir Immune Defic Syndr271
Safety and immunogenicity of the quadrivalent human papillomavirus vaccine in HIV-1-infected men.Wilkin, Timothy ; Lee, Jeannette Y ; Lensing, Shelly Y ; Stier, Elizabeth A ; Goldstone, Stephen E ; Berry, J Michael ; Jay, Naomi ; Aboulafia, David ; Cohn, David L ; Einstein, Mark H ; Saah, Alfred ; Mitsuyasu, Ronald T ; Palefsky, Joel M2010 Oct 15J Infect Dis8202
Safety and immunogenicity of therapeutic DNA vaccination in individuals treated with antiretroviral therapy during acute/early HIV-1 infection.Rosenberg, Eric S ; Graham, Barney S ; Chan, Ellen S ; Bosch, Ronald J ; Stocker, Vicki ; Maenza, Janine ; Markowitz, Martin ; Little, Susan ; Sax, Paul E ; Collier, Ann C ; Nabel, Gary ; Saindon, Suzanne ; Flynn, Theresa ; Kuritzkes, Daniel ; Barouch, Dan H ; AIDS Clinical Trials Group A5187 Team2010PLoS One55
Safety and tolerability of depot medroxyprogesterone acetate among HIV-infected women on antiretroviral therapy: ACTG A5093.Watts, D Heather ; Park, Jeong-Gun ; Cohn, Susan E ; Yu, Song ; Hitti, Jane ; Stek, Alice ; Clax, Pamela A ; Muderspach, Laila ; Lertora, Juan J L2008 FebContraception277
Safety, tolerability, and immunogenicity of repeated doses of dermavir, a candidate therapeutic HIV vaccine, in HIV-infected patients receiving combination antiretroviral therapy: results of the ACTG 5176 trial.Rodriguez, Benigno ; Asmuth, David M ; Matining, Roy M ; Spritzler, John ; Jacobson, Jeffrey M ; Mailliard, Robbie B ; Li, Xiao-Dong ; Martinez, Ana I ; Tenorio, Allan R ; Lori, Franco ; Lisziewicz, Julianna ; Yesmin, Suria ; Rinaldo, Charles R ; Pollard, Richard B2013 Dec 1J Acquir Immune Defic Syndr464
Safety, tolerability, and mechanisms of antiretroviral activity of pegylated interferon Alfa-2a in HIV-1-monoinfected participants: a phase II clinical trial.Asmuth, David M ; Murphy, Robert L ; Rosenkranz, Susan L ; Lertora, Juan J L ; Kottilil, Shyam ; Cramer, Yoninah ; Chan, Ellen S ; Schooley, Robert T ; Rinaldo, Charles R ; Thielman, Nathan ; Li, Xiao-Dong ; Wahl, Sharon M ; Shore, Jessica ; Janik, Jennifer ; Lempicki, Richard A ; Simpson, Yaa ; Pollard, Richard B ; AIDS Clinical Trials Gr2010 Jun 1J Infect Dis11201
Safety, tolerability, and pharmacokinetic interactions of the antituberculous agent TMC207 (bedaquiline) with efavirenz in healthy volunteers: AIDS Clinical Trials Group Study A5267.Dooley, Kelly E ; Park, Jeong-Gun ; Swindells, Susan ; Allen, Reena ; Haas, David W ; Cramer, Yoninah ; Aweeka, Francesca ; Wiggins, Ilene ; Gupta, Amita ; Lizak, Patricia ; Qasba, Sonia ; van Heeswijk, Rolf ; Flexner, Charles ; ACTG 5267 Study Team2012 Apr 15J Acquir Immune Defic Syndr559
Safety, tolerability, pharmacokinetics, and efficacy of an interleukin-2 agonist among HIV-infected patients receiving highly active antiretroviral therapy.Davey, Richard T ; Pertel, Peter E ; Benson, Alice ; Cassell, Delanie J ; Gazzard, Brian G ; Holodniy, Mark ; Lalezari, Jacob P ; Levy, Yves ; Mitsuyasu, Ronald T ; Palella, Frank J ; Pollard, Richard B ; Rajagopalan, Prabhu ; Saag, Michael S ; Salata, Robert A ; Sha, Beverly E ; Choudhri, Shurjeel2008 FebJ Interferon Cytokine Res228
Screening for pulmonary tuberculosis in HIV-infected individuals: AIDS Clinical Trials Group Protocol A5253.Swindells, S ; Komarow, L ; Tripathy, S ; Cain, K P ; MacGregor, R R ; Achkar, J M ; Gupta, A ; Veloso, V G ; Asmelash, A ; Omoz-Oarhe, A E ; Gengiah, S ; Lalloo, U ; Allen, R ; Shiboski, C ; Andersen, J ; Qasba, S S ; Katzenstein, D K ; AIDS Clinical Trials Group 5253 Study Team2013 AprInt J Tuberc Lung Dis417
Screening for UGT1A1 Genotype in Study A5257 Would Have Markedly Reduced Premature Discontinuation of Atazanavir for Hyperbilirubinemia.Vardhanabhuti, Saran ; Ribaudo, Heather J ; Landovitz, Raphael J ; Ofotokun, Ighovwerha ; Lennox, Jeffrey L ; Currier, Judith S ; Olson, Lana M ; Haas, David W2015 SepOpen Forum Infect Dis32
Second assessment of NeuroAIDS in Africa.Robertson, Kevin ; Kopnisky, Kathy ; Hakim, James ; Merry, Concepta ; Nakasujja, Noeline ; Hall, Colin ; Traore, Moussa ; Sacktor, Ned ; Clifford, David ; Newton, Charles ; Van Rie, Annelies ; Holding, Penny ; Clements, Janice ; Zink, Christine ; Mielk, Jens ; Hosseinipour, Mina ; Lalloo, Umesh ; Amod, Farida ; Marra, Christina ; Evans, Sc2008 AprJ Neurovirol214
Secondary metabolism pathway polymorphisms and plasma efavirenz concentrations in HIV-infected adults with CYP2B6 slow metabolizer genotypes.Haas, David W ; Kwara, Awewura ; Richardson, Danielle M ; Baker, Paxton ; Papageorgiou, Ioannis ; Acosta, Edward P ; Morse, Gene D ; Court, Michael H2014 AugJ Antimicrob Chemother869
Selection and persistence of non-nucleoside reverse transcriptase inhibitor-resistant HIV-1 in patients starting and stopping non-nucleoside therapy.Palmer, Sarah ; Boltz, Valerie ; Maldarelli, Frank ; Kearney, Mary ; Halvas, Elias K ; Rock, Diane ; Falloon, Judith ; Davey, Richard T ; Dewar, Robin L ; Metcalf, Julia A ; Mellors, John W ; Coffin, John M2006 Mar 21AIDS520
Selective Loss of Early Differentiated, Highly Functional PD1high CD4 T Cells with HIV Progression.Paris, Robert M ; Petrovas, Constantinos ; Ferrando-Martinez, Sara ; Moysi, Eirini ; Boswell, Kristin L ; Archer, Eva ; Yamamoto, Takuya ; Ambrozak, David ; Casazza, Joseph P ; Haubrich, Richard ; Connors, Mark ; Ake, Julie ; Kim, Jerome H ; Koup, Richard A2015PLoS One1210
Selegiline and oxidative stress in HIV-associated cognitive impairment.Schifitto, G ; Yiannoutsos, C T ; Ernst, T ; Navia, B A ; Nath, A ; Sacktor, N ; Anderson, C ; Marra, C M ; Clifford, D B ; ACTG 5114 Team2009 Dec 8Neurology2373
Selegiline transdermal system (STS) for HIV-associated cognitive impairment: open-label report of ACTG 5090.Evans, Scott R ; Yeh, Tzu-min ; Sacktor, Ned ; Clifford, David B ; Simpson, David ; Miller, Eric N ; Ellis, Ronald J ; Valcour, Victor ; Marra, Christina M ; Millar, Linda ; Schifitto, Giovanni ; AIDS Clinical Trials Group and the Neurologic AIDS Research Consortium2007 Nov-DecHIV Clin Trials68
Sensitive assay for determining plasma tenofovir concentrations by LC/MS/MS.Delahunty, Tom ; Bushman, Lane ; Fletcher, Courtney V2006 Jan 2J Chromatogr B Analyt Technol Biomed Life Sci1830
Serosorting can potentially increase HIV transmissions.Butler, David M ; Smith, Davey M2007 May 31AIDS921
The setpoint study (ACTG A5217): effect of immediate versus deferred antiretroviral therapy on virologic set point in recently HIV-1-infected individuals.Hogan, Christine M ; Degruttola, Victor ; Sun, Xin ; Fiscus, Susan A ; Del Rio, Carlos ; Hare, C Bradley ; Markowitz, Martin ; Connick, Elizabeth ; Macatangay, Bernard ; Tashima, Karen T ; Kallungal, Beatrice ; Camp, Rob ; Morton, Tia ; Daar, Eric S ; Little, Susan ; A5217 Study Team2012 Jan 1J Infect Dis1205
Sevelamer does not decrease lipopolysaccharide or soluble CD14 levels but decreases soluble tissue factor, low-density lipoprotein (LDL) cholesterol, and oxidized LDL cholesterol levels in individuals with untreated HIV infection.Sandler, Netanya G ; Zhang, Xinyan ; Bosch, Ronald J ; Funderburg, Nicholas T ; Choi, Andrew I ; Robinson, Janet K ; Fine, Derek M ; Coombs, Robert W ; Jacobson, Jeffrey M ; Landay, Alan L ; Douek, Daniel C ; Tressler, Randall ; Read, Sarah W ; Wilson, Cara C ; Deeks, Steven G ; Lederman, Michael M ; Gandhi, Rajesh T ; AIDS Clinical Trials2014 Nov 15J Infect Dis10210
Sex differences in atazanavir pharmacokinetics and associations with time to clinical events: AIDS Clinical Trials Group Study A5202.Venuto, Charles S ; Mollan, Katie ; Ma, Qing ; Daar, Eric S ; Sax, Paul E ; Fischl, Margaret ; Collier, Ann C ; Smith, Kimberly Y ; Tierney, Camlin ; Morse, Gene D2014 DecJ Antimicrob Chemother1269
Sex differences in lopinavir and ritonavir pharmacokinetics among HIV-infected women and men.Umeh, Obi C ; Currier, Judith S ; Park, Jeong-Gun ; Cramer, Yoninah ; Hermes, Ashwaq E ; Fletcher, Courtney V2011 DecJ Clin Pharmacol1251
Sex differences in the Toll-like receptor-mediated response of plasmacytoid dendritic cells to HIV-1.Meier, Angela ; Chang, J Judy ; Chan, Ellen S ; Pollard, Richard B ; Sidhu, Harlyn K ; Kulkarni, Smita ; Wen, Tom Fang ; Lindsay, Robert J ; Orellana, Liliana ; Mildvan, Donna ; Bazner, Suzane ; Streeck, Hendrik ; Alter, Galit ; Lifson, Jeffrey D ; Carrington, Mary ; Bosch, Ronald J ; Robbins, Gregory K ; Altfeld, Marcus2009 AugNat Med815
Sex-associated differences in pre-antiretroviral therapy plasma HIV-1 RNA in diverse areas of the world vary by CD4(+) T-cell count.Grinsztejn, Beatriz ; Smeaton, Laura ; Barnett, Ronald ; Klingman, Karin ; Hakim, James ; Flanigan, Timothy ; Kumarasamy, N ; Campbell, Thomas ; Currier, Judith ; PEARLS study team of the ACTG2011Antivir Ther716
Sex-related Differences in Inflammatory and Immune Activation Markers before and after combined Antiretroviral Therapy Initiation.Mathad, Jyoti S ; Gupte, Nikhil ; Balagopal, Ashwin ; Asmuth, David ; Hakim, James ; Santos, Breno ; Riviere, Cynthia ; Hosseinipour, Mina ; Sugandhavesa, Patcharaphan ; Infante, Rosa ; Pillay, Sandy ; Cardoso, Sandra W ; Mwelase, Noluthando ; Pawar, Jyoti ; Berendes, Sima ; Kumarasamy, Nagalingeswaran ; Andrade, Bruno B ; Campbell, Thomas2016 May 27J Acquir Immune Defic Syndr
Short-term ezetimibe is well tolerated and effective in combination with statin therapy to treat elevated LDL cholesterol in HIV-infected patients.Chow, Dominic ; Chen, Huichao ; Glesby, Marshall J ; Busti, Anthony ; Souza, Scott ; Andersen, Janet ; Kohrs, Sharon ; Wu, Julia ; Koletar, Susan L2009 Oct 23AIDS1623
Simian immunodeficiency virus engrafted with human immunodeficiency virus type 1 (HIV-1)-specific epitopes: replication, neutralization, and survey of HIV-1-positive plasma.Yuste, Eloisa ; Sanford, Hannah B ; Carmody, Jill ; Bixby, Jacqueline ; Little, Susan ; Zwick, Michael B ; Greenough, Tom ; Burton, Dennis R ; Richman, Douglas D ; Desrosiers, Ronald C ; Johnson, Welkin E2006 MarJ Virol680
Simplification of the research diagnosis of HIV-associated sensory neuropathy.Evans, Scott R ; Clifford, David B ; Kitch, Douglas W ; Goodkin, Karl ; Schifitto, Giovanni ; McArthur, Justin C ; Simpson, David M2008 Nov-DecHIV Clin Trials69
Site nurse-initiated adherence and symptom support telephone calls for HIV-positive individuals starting antiretroviral therapy, ACTG 5031: substudy of ACTG 384.Robbins, Gregory K ; Testa, Marcia A ; Su, Max ; Safren, Steven A ; Morse, Gene ; Lammert, Sara ; Shafer, Robert W ; Reynolds, Nancy R ; Chesney, Margaret A2013 Sep-OctHIV Clin Trials514
The size of the expressed HIV reservoir predicts timing of viral rebound after treatment interruption.Li, Jonathan Z ; Etemad, Behzad ; Ahmed, Hayat ; Aga, Evgenia ; Bosch, Ronald J ; Mellors, John W ; Kuritzkes, Daniel R ; Lederman, Michael M ; Para, Michael ; Gandhi, Rajesh T2016 Jan 28AIDS330
Soluble Levels of Receptor for Advanced Glycation Endproducts (RAGE) and Progression of Atherosclerosis in Individuals Infected with Human Immunodeficiency Virus: ACTG NWCS 332.Danoff, Ann ; Kendall, Michelle A ; Currier, Judith S ; Kelesidis, Theodoros ; Schmidt, Ann Marie ; Aberg, Judith A2016 AugInflammation439
Soluble markers of inflammation and coagulation but not T-cell activation predict non-AIDS-defining morbid events during suppressive antiretroviral treatment.Tenorio, Allan R ; Zheng, Yu ; Bosch, Ronald J ; Krishnan, Supriya ; Rodriguez, Benigno ; Hunt, Peter W ; Plants, Jill ; Seth, Arjun ; Wilson, Cara C ; Deeks, Steven G ; Lederman, Michael M ; Landay, Alan L2014 Oct 15J Infect Dis8210
S-phase entry leads to cell death in circulating T cells from HIV-infected persons.Sieg, Scott F ; Bazdar, Douglas A ; Lederman, Michael M2008 JunJ Leukoc Biol683
Statin therapy and changes in hip circumference among HIV-infected participants in the ALLRT Cohort.Brown, Todd T ; Smurzynski, Marlene ; Wu, Kunling ; Bosch, Ronald J ; McComsey, Grace A2009Antivir Ther614
Statistical determination of threshold for cellular division in the CFSE-labeling assay.Liu, Dacheng ; Yu, Jie ; Chen, Huiyuan ; Reichman, Richard ; Wu, Hulin ; Jin, Xia2006 May 30J Immunol Methods1-2312
A statistical framework for quantile equivalence clinical trials with application to pharmacokinetic studies that bridge from HIV-infected adults to children.Pei, Lixia ; Hughes, Michael D2008 DecBiometrics464
Substitution of nevirapine because of efavirenz toxicity in AIDS clinical trials group A5095.Schouten, Jeffrey T ; Krambrink, Amy ; Ribaudo, Heather J ; Kmack, Anne ; Webb, Nancy ; Shikuma, Cecilia ; Kuritzkes, Daniel R ; Gulick, Roy M2010 Mar 1Clin Infect Dis550
Suppression of HIV-1 replication by antiretroviral therapy improves renal function in persons with low CD4 cell counts and chronic kidney disease.Kalayjian, Robert C ; Franceschini, Nora ; Gupta, Samir K ; Szczech, Lynda A ; Mupere, Ezekiel ; Bosch, Ronald J ; Smurzynski, Marlene ; Albert, Jeffrey M2008 Feb 19AIDS422
Surface expression patterns of negative regulatory molecules identify determinants of virus-specific CD8+ T-cell exhaustion in HIV infection.Yamamoto, Takuya ; Price, David A ; Casazza, Joseph P ; Ferrari, Guido ; Nason, Martha ; Chattopadhyay, Pratip K ; Roederer, Mario ; Gostick, Emma ; Katsikis, Peter D ; Douek, Daniel C ; Haubrich, Richard ; Petrovas, Constantinos ; Koup, Richard A2011 May 5Blood18117
Sustained long-term antiviral maintenance therapy in HCV/HIV-coinfected patients (SLAM-C).Sherman, Kenneth E ; Andersen, Janet W ; Butt, Adeel A ; Umbleja, Triin ; Alston, Beverly ; Koziel, Margaret J ; Peters, Marion G ; Sulkowski, Mark ; Goodman, Zachary D ; Chung, Raymond T ; AIDS Clinical Trials Group A5178 Study Team2010 Dec 15J Acquir Immune Defic Syndr555
Switching to a protease inhibitor-containing, nucleoside-sparing regimen (lopinavir/ritonavir plus efavirenz) increases limb fat but raises serum lipid levels: results of a prospective randomized trial (AIDS clinical trial group 5125s).Tebas, Pablo ; Zhang, Jiameng ; Yarasheski, Kevin ; Evans, Scott ; Fischl, Margaret A ; Shevitz, Abby ; Feinberg, Judith ; Collier, Ann C ; Shikuma, Cecilia ; Brizz, Barbara ; Sattler, Fred ; AIDS Clinical Trials Group (ACTG)2007 Jun 1J Acquir Immune Defic Syndr245