ACTG Publications

TitleAuthorsDateJournalIssueVolume
ACTG A5353: A Pilot Study of Dolutegravir Plus Lamivudine for Initial Treatment of Human Immunodeficiency Virus-1 (HIV-1)-infected Participants With HIV-1 RNA <500000 Copies/mL.Taiwo, Babafemi O ; Zheng, Lu ; Stefanescu, Andrei ; Nyaku, Amesika ; Bezins, Baiba ; Wallis, Carole L ; Godfrey, Catherine ; Sax, Paul E ; Acosta, Edward ; Haas, David ; Smith, Kimberly Y ; Sha, Beverly ; Van Dam, Cornelius ; Gulick, Roy M2018 May 17Clin Infect Dis1166
Associations of T cell activation and inflammatory biomarkers with virological response to darunavir/ritonavir plus raltegravir therapy.Taiwo, Babafemi ; Matining, Roy M ; Zheng, Lu ; Lederman, Michael M ; Rinaldo, Charles R ; Kim, Peter S ; Berzins, Baiba I ; Kuritzkes, Daniel R ; Jennings, Amy ; Eron, Joseph J ; Wilson, Cara C2013 AugJ Antimicrob Chemother868
Binge drinking is associated with differences in weekday and weekend adherence in HIV-infected individuals.De Boni, Raquel B ; Zheng, Lu ; Rosenkranz, Susan L ; Sun, Xin ; Lavenberg, Jeffrey ; Cardoso, Sandra W ; Grinsztejn, Beatriz ; La Rosa, Alberto ; Pierre, Samuel ; Severe, Patrice ; Cohn, Susan E ; Collier, Ann C ; Gross, Robert2016 Feb 1Drug Alcohol Depend159
Comparison of illumina and 454 deep sequencing in participants failing raltegravir-based antiretroviral therapy.Li, Jonathan Z ; Chapman, Brad ; Charlebois, Patrick ; Hofmann, Oliver ; Weiner, Brian ; Porter, Alyssa J ; Samuel, Reshmi ; Vardhanabhuti, Saran ; Zheng, Lu ; Eron, Joseph ; Taiwo, Babafemi ; Zody, Michael C ; Henn, Matthew R ; Kuritzkes, Daniel R ; Hide, Winston ; ACTG A5262 Study Team ; Wilson, Cara C ; Berzins, Baiba I ; Acosta, Edward2014PLoS One39
Comparison of immunologic assays for detecting immune responses in HIV immunotherapeutic studies: AIDS Clinical Trials Group Trial A5181.Macatangay, Bernard J C ; Zheng, Lu ; Rinaldo, Charles R ; Landay, Alan L ; Pollard, Richard B ; Pahwa, Savita ; Lederman, Michael M ; Bucy, R Pat2010 SepClin Vaccine Immunol917
The design of single-arm clinical trials of combination antiretroviral regimens for treatment-naive HIV-infected patients.Zheng, Lu ; Rosenkranz, Susan L ; Taiwo, Babafemi ; Para, Michael F ; Eron, Joseph J ; Hughes, Michael D2013 AprAIDS Res Hum Retroviruses429
Dolutegravir plus lamivudine for initial treatment of HIV-1-infected participants with HIV-1 RNA <500‚ÄČ000 copies/mL: week 48 outcomes from ACTG 5353.Nyaku, Amesika N ; Zheng, Lu ; Gulick, Roy M ; Olefsky, Maxine ; Berzins, Baiba ; Wallis, Carole L ; Godfrey, Catherine ; Sax, Paul E ; Acosta, Edward P ; Haas, David W ; Smith, Kimberly Y ; Sha, Beverly E ; Van Dam, Cornelius N ; Taiwo, Babafemi O ; ACTG A5353 Study Team2019 Jan 18J Antimicrob Chemother
Effect of highly active antiretroviral therapy on viral burden in the lungs of HIV-infected subjects.Twigg Iii, Homer L ; Weiden, Michael ; Valentine, Fred ; Schnizlein-Bick, Carol T ; Bassett, Roland ; Zheng, Lu ; Wheat, Joseph ; Day, Richard B ; Rominger, Helen ; Collman, Ronald G ; Fox, Lawrence ; Brizz, Barbara ; Dragavon, Joan ; Coombs, Robert W ; Bucy, R Pat ; AIDS Clinical Trials Group Protocol 723 Team2008 Jan 1J Infect Dis1197
The effect of raltegravir intensification on low-level residual viremia in HIV-infected patients on antiretroviral therapy: a randomized controlled trial.Gandhi, Rajesh T ; Zheng, Lu ; Bosch, Ronald J ; Chan, Ellen S ; Margolis, David M ; Read, Sarah ; Kallungal, Beatrice ; Palmer, Sarah ; Medvik, Kathy ; Lederman, Michael M ; Alatrakchi, Nadia ; Jacobson, Jeffrey M ; Wiegand, Ann ; Kearney, Mary ; Coffin, John M ; Mellors, John W ; Eron, Joseph J ; AIDS Clinical Trials Group A5244 team2010PLoS Med87
Efficacy of a nucleoside-sparing regimen of darunavir/ritonavir plus raltegravir in treatment-naive HIV-1-infected patients (ACTG A5262).Taiwo, Babafemi ; Zheng, Lu ; Gallien, Sebastien ; Matining, Roy M ; Kuritzkes, Daniel R ; Wilson, Cara C ; Berzins, Baiba I ; Acosta, Edward P ; Bastow, Barbara ; Kim, Peter S ; Eron, Joseph J ; ACTG A5262 Team2011 Nov 13AIDS1725
Factors associated with CD8+ T-cell activation in HIV-1-infected patients on long-term antiretroviral therapy.Zheng, Lu ; Taiwo, Babafemi ; Gandhi, Rajesh T ; Hunt, Peter W ; Collier, Ann C ; Flexner, Charles ; Bosch, Ronald J2014 Oct 1J Acquir Immune Defic Syndr267
Frequency of Antiretroviral Resistance Mutations among Infants Exposed to Single-Dose Nevirapine and Short Course Maternal Antiretroviral Regimens: ACTG A5207.Hitti, Jane ; Halvas, Elias K ; Zheng, Lu ; Panousis, Constantinos G ; Kabanda, Joseph ; Taulo, Frank ; Kumarasamy, Nagalingeswaran ; Pape, Jean William ; Lalloo, Umesh ; Sprenger, Heather ; Klingman, Karin L ; Chan, Ellen S ; McMahon, Deborah ; Mellors, John W2014 NovJ AIDS Clin Res115
Greater suppression of nevirapine resistance with 21- vs 7-day antiretroviral regimens after intrapartum single-dose nevirapine for prevention of mother-to-child transmission of HIV.McMahon, Deborah K ; Zheng, Lu ; Hitti, Jane ; Chan, Ellen S ; Halvas, Elias K ; Hong, Feiyu ; Kabanda, Joseph ; Taulo, Frank ; Kumarasamy, Nagalingeswaran ; Bonhomme, Jerry ; Wallis, Carole L ; Klingman, Karin L ; Hughes, Michael D ; Mellors, John W2013 AprClin Infect Dis756
Measurement of antiretroviral drugs in the lungs of HIV-infected patients.Twigg, Homer L ; Schnizlein-Bick, Carol T ; Weiden, Michael ; Valentine, Fred ; Wheat, Joseph ; Day, Richard B ; Rominger, Helen ; Zheng, Lu ; Collman, Ronald G ; Coombs, Robert W ; Bucy, R Pat ; Rezk, Naser L ; Kashuba, Angela Dm2010 Mar 1HIV Ther24
No effect of raltegravir intensification on viral replication markers in the blood of HIV-1-infected patients receiving antiretroviral therapy.Gandhi, Rajesh T ; Coombs, Robert W ; Chan, Ellen S ; Bosch, Ronald J ; Zheng, Lu ; Margolis, David M ; Read, Sarah ; Kallungal, Beatrice ; Chang, Ming ; Goecker, Erin A ; Wiegand, Ann ; Kearney, Mary ; Jacobson, Jeffrey M ; D'Aquila, Richard ; Lederman, Michael M ; Mellors, John W ; Eron, Joseph J ; AIDS Clinical Trials Group (ACTG) A52442012 Mar 1J Acquir Immune Defic Syndr359
Partner-Focused Adherence Intervention for Second-line Antiretroviral Therapy: A Multinational Randomized Trial (ACTG A5234).Gross, Robert ; Zheng, Lu ; La Rosa, Alberto ; Sun, Xin ; Rosenkranz, Susan L ; Cardoso, Sandra Wagner ; Ssali, Francis ; Camp, Rob ; Godfrey, Catherine ; Cohn, Susan E ; Robbins, Gregory K ; Chisada, Anthony ; Wallis, Carole L ; Reynolds, Nancy R ; Lu, Darlene ; Safren, Steven A ; Hosey, Lara ; Severe, Patrice ; Collier, Ann C2015 Jan 1Lancet HIV12
Predictors of residual viraemia in patients on long-term suppressive antiretroviral therapy.Zheng, Lu ; Bosch, Ronald J ; Chan, Ellen S ; Read, Sarah ; Kearney, Mary ; Margolis, David M ; Mellors, John W ; Eron, Joseph J ; Gandhi, Rajesh T ; DS Clinical Trials Group (ACTG) A5244 Team2013Antivir Ther118
Quality of life among HIV-infected individuals failing first-line antiretroviral therapy in resource-limited settings.Torres, Thiago S ; Harrison, Linda J ; La Rosa, Alberto M ; Lavenberg, Jeffrey A ; Zheng, Lu ; Safren, Steven A ; Ngongondo, McNeil ; Poongulali, Selvamuthu ; Matoga, Mitch ; Samaneka, Wadzanai ; Collier, Ann C ; Hughes, Michael D2018 AugAIDS Care830
Quality of life improvement in resource-limited settings after one year of second-line antiretroviral therapy use among adult men and women.Torres, Thiago S ; Harrison, Linda J ; La Rosa, Alberto M ; Cardoso, Sandra W ; Zheng, Lu ; Ngongondo, McNeil ; Some, Fatma ; Lalloo, Umesh G ; Mwelase, Thando ; Collier, Ann C ; Hughes, Michael D ; AIDS Clinical Trials Group (ACTG) A5273 Study Group2018 Mar 13AIDS532
Raltegravir in second-line antiretroviral therapy in resource-limited settings (SELECT): a randomised, phase 3, non-inferiority study.La Rosa, Alberto M ; Harrison, Linda J ; Taiwo, Babafemi ; Wallis, Carole L ; Zheng, Lu ; Kim, Peter ; Kumarasamy, Nagalingeswaran ; Hosseinipour, Mina C ; Jarocki, Bernadette ; Mellors, John W ; Collier, Ann C ; ACTG A5273 Study Group2016 JunLancet HIV63
Randomized Clinical Trial to Assess the Impact of the Broadly Neutralizing HIV-1 Monoclonal Antibody VRC01 on HIV-1 Persistence in Individuals on Effective ART.Riddler, Sharon A ; Zheng, Lu ; Durand, Christine M ; Ritz, Justin ; Koup, Richard A ; Ledgerwood, Julie ; Bailer, Robert T ; Koletar, Susan L ; Eron, Joseph J ; Keefer, Michael C ; Macatangay, Bernard J C ; Cyktor, Joshua C ; Mellors, John W ; AIDS Clinical Trials Group A5342 Protocol Team2018 OctOpen Forum Infect Dis105
A randomized controlled trial of palifermin (recombinant human keratinocyte growth factor) for the treatment of inadequate CD4+ T-lymphocyte recovery in patients with HIV-1 infection on antiretroviral therapy.Jacobson, Jeffrey M ; Wang, Hongying ; Bordi, Rebeka ; Zheng, Lu ; Gross, Barry H ; Landay, Alan L ; Spritzler, John ; Routy, Jean-Pierre ; Benson, Constance ; Aberg, Judith ; Tebas, Pablo ; Haas, David W ; Tiu, Jennifer ; Coughlin, Kristine ; Purdue, Lynette ; Sekaly, Rafick-Pierre ; AIDS Clinical Trials Group (ACTG) A5212 Protocol Team2014 Aug 1J Acquir Immune Defic Syndr466
Relationship of HIV reservoir characteristics with immune status and viral rebound kinetics in an HIV therapeutic vaccine study.Li, Jonathan Z ; Heisey, Andrea ; Ahmed, Hayat ; Wang, Hongying ; Zheng, Lu ; Carrington, Mary ; Wrin, Terri ; Schooley, Robert T ; Lederman, Michael M ; Kuritzkes, Daniel R ; ACTG A5197 Study Team2014 Nov 28AIDS1828
The Safety and Immunogenicity of an Interleukin-12-Enhanced Multiantigen DNA Vaccine Delivered by Electroporation for the Treatment of HIV-1 Infection.Jacobson, Jeffrey M ; Zheng, Lu ; Wilson, Cara C ; Tebas, Pablo ; Matining, Roy M ; Egan, Michael A ; Eldridge, John ; Landay, Alan L ; Clifford, David B ; Luetkemeyer, Anne F ; Tiu, Jennifer ; Martinez, Ana L ; Janik, Jennifer ; Spitz, Teresa A ; Hural, John ; McElrath, Juliana ; Frahm, Nicole ; ACTG A5281 Protocol Team2016 Feb 1J Acquir Immune Defic Syndr271
Transcriptional Changes in CD8(+) T Cells During Antiretroviral Therapy Intensified With Raltegravir.Ouyang, Zhengyu ; Buzon, Maria J ; Zheng, Lu ; Sun, Hong ; Yu, Xu G ; Bosch, Ronald J ; Mellors, John W ; Eron, Joseph J ; Gandhi, Rajesh T ; Lichterfeld, Mathias2015 AprOpen Forum Infect Dis22
Treatment with recombinant growth hormone is associated with modest improvement in CD4 lymphocyte reconstitution in HIV-infected persons on antiretroviral therapy: results of ACTG A5174.Smith, Kimberly ; Zheng, Lu ; Bosch, Ronald ; Margolis, David M ; Tenorio, Allan ; Napolitano, Laura ; Saag, Michael ; Connick, Elizabeth ; Gross, Barry ; Francis, Isaac ; Valdez, Hernan ; Muurahainen, Norma ; Stocker, Vicky ; Pollard, Richard2010 AprAIDS Res Hum Retroviruses426