ACTG Publications

TitleAuthorsDateJournalIssueVolume
Brief Report: Relationship Among Viral Load Outcomes in HIV Treatment Interruption Trials.Treasure, Graham C ; Aga, Evgenia ; Bosch, Ronald J ; Mellors, John W ; Kuritzkes, Daniel R ; Para, Michael ; Gandhi, Rajesh T ; Li, Jonathan Z2016 Jul 1J Acquir Immune Defic Syndr372
CD8+ T-cell activation in HIV-1-infected patients experiencing transient low-level viremia during antiretroviral therapy.Taiwo, Babafemi ; Hunt, Peter W ; Gandhi, Rajesh T ; Ellingson, Andrew ; McKenna, Matthew ; Jacobson, Jeffrey M ; Gripshover, Barbara ; Bosch, Ronald J2013 May 1J Acquir Immune Defic Syndr163
Continued Slow Decay of the Residual Plasma Viremia Level in HIV-1-Infected Adults Receiving Long-term Antiretroviral Therapy.Riddler, Sharon A ; Aga, Evgenia ; Bosch, Ronald J ; Bastow, Barbara ; Bedison, Margaret ; Vagratian, David ; Vaida, Florin ; Eron, Joseph J ; Gandhi, Rajesh T ; Mellors, John W ; ACTG A5276s Protocol Team2016 Feb 15J Infect Dis4213
The Control of HIV After Antiretroviral Medication Pause (CHAMP) Study: Posttreatment Controllers Identified From 14 Clinical Studies.Namazi, Golnaz ; Fajnzylber, Jesse M ; Aga, Evgenia ; Bosch, Ronald J ; Acosta, Edward P ; Sharaf, Radwa ; Hartogensis, Wendy ; Jacobson, Jeffrey M ; Connick, Elizabeth ; Volberding, Paul ; Skiest, Daniel ; Margolis, David ; Sneller, Michael C ; Little, Susan J ; Gianella, Sara ; Smith, Davey M ; Kuritzkes, Daniel R ; Gulick, Roy M ; Mello2018 Nov 05J Infect Dis12218
Cumulative Antiretroviral Exposure Measured in Hair Is Not Associated With Measures of HIV Persistence or Inflammation Among Individuals on Suppressive ART.Gandhi, Monica ; Gandhi, Rajesh T ; Stefanescu, Andrei ; Bosch, Ronald J ; Cyktor, Joshua C ; Horng, Howard ; Louie, Alexander ; Phung, Nhi ; Eron, Joseph J ; Hogg, Evelyn ; Macatangay, Bernard J C ; Hensel, Christopher ; Fletcher, Courtney V ; Mellors, John W ; McMahon, Deborah K ; A5321 Team2018 Jun 20J Infect Dis2218
Effect of baseline- and treatment-related factors on immunologic recovery after initiation of antiretroviral therapy in HIV-1-positive subjects: results from ACTG 384.Gandhi, Rajesh T ; Spritzler, John ; Chan, Ellen ; Asmuth, David M ; Rodriguez, Benigno ; Merigan, Thomas C ; Hirsch, Martin S ; Shafer, Robert W ; Robbins, Gregory K ; Pollard, Richard B ; ACTG 384 Team2006 Aug 1J Acquir Immune Defic Syndr442
The effect of raltegravir intensification on low-level residual viremia in HIV-infected patients on antiretroviral therapy: a randomized controlled trial.Gandhi, Rajesh T ; Zheng, Lu ; Bosch, Ronald J ; Chan, Ellen S ; Margolis, David M ; Read, Sarah ; Kallungal, Beatrice ; Palmer, Sarah ; Medvik, Kathy ; Lederman, Michael M ; Alatrakchi, Nadia ; Jacobson, Jeffrey M ; Wiegand, Ann ; Kearney, Mary ; Coffin, John M ; Mellors, John W ; Eron, Joseph J ; AIDS Clinical Trials Group A5244 team2010PLoS Med87
Effect of Short-Term Antiretroviral Therapy Interruption on Levels of Integrated HIV DNA.Strongin, Zachary ; Sharaf, Radwa ; VanBelzen, D Jake ; Jacobson, Jeffrey M ; Connick, Elizabeth ; Volberding, Paul ; Skiest, Daniel J ; Gandhi, Rajesh T ; Kuritzkes, Daniel R ; O'Doherty, Una ; Li, Jonathan Z2018 06 15J Virol1292
Factors associated with CD8+ T-cell activation in HIV-1-infected patients on long-term antiretroviral therapy.Zheng, Lu ; Taiwo, Babafemi ; Gandhi, Rajesh T ; Hunt, Peter W ; Collier, Ann C ; Flexner, Charles ; Bosch, Ronald J2014 Oct 1J Acquir Immune Defic Syndr267
HIV Salvage Therapy Does Not Require Nucleoside Reverse Transcriptase Inhibitors: A Randomized, Controlled Trial.Tashima, Karen T ; Smeaton, Laura M ; Fichtenbaum, Carl J ; Andrade, Adriana ; Eron, Joseph J ; Gandhi, Rajesh T ; Johnson, Victoria A ; Klingman, Karin L ; Ritz, Justin ; Hodder, Sally ; Santana, Jorge L ; Wilkin, Timothy ; Haubrich, Richard H ; A5241 Study Team2015 Dec 15Ann Intern Med12163
HIV-1 DNA decay dynamics in blood during more than a decade of suppressive antiretroviral therapy.Besson, Guillaume J ; Lalama, Christina M ; Bosch, Ronald J ; Gandhi, Rajesh T ; Bedison, Margaret A ; Aga, Evgenia ; Riddler, Sharon A ; McMahon, Deborah K ; Hong, Feiyu ; Mellors, John W2014 Nov 1Clin Infect Dis959
HIV-1 proviral landscapes distinguish posttreatment controllers from noncontrollers.Sharaf, Radwa ; Lee, Guinevere Q ; Sun, Xiaoming ; Etemad, Behzad ; Aboukhater, Layla M ; Hu, Zixin ; Brumme, Zabrina L ; Aga, Evgenia ; Bosch, Ronald J ; Wen, Ying ; Namazi, Golnaz ; Gao, Ce ; Acosta, Edward P ; Gandhi, Rajesh T ; Jacobson, Jeffrey M ; Skiest, Daniel ; Margolis, David M ; Mitsuyasu, Ronald ; Volberding, Paul ; Connick, El2018 Aug 31J Clin Invest9128
Impact of HLA Class I Alleles on Timing of HIV Rebound After Antiretroviral Treatment Interruption.Park, You Jeong ; Etemad, Behzad ; Ahmed, Hayat ; Naranbhai, Vivek ; Aga, Evgenia ; Bosch, Ronald J ; Mellors, John W ; Kuritzkes, Daniel R ; Para, Michael ; Gandhi, Rajesh T ; Carrington, Mary ; Li, Jonathan Z2017Pathog Immun32
Incomplete reconstitution of T cell subsets on combination antiretroviral therapy in the AIDS Clinical Trials Group protocol 384.Robbins, Gregory K ; Spritzler, John G ; Chan, Ellen S ; Asmuth, David M ; Gandhi, Rajesh T ; Rodriguez, Benigno A ; Skowron, Gail ; Skolnik, Paul R ; Shafer, Robert W ; Pollard, Richard B ; AIDS Clinical Trials Group 384 Team2009 Feb 1Clin Infect Dis348
Levels of HIV-1 persistence on antiretroviral therapy are not associated with markers of inflammation or activation.Gandhi, Rajesh T ; McMahon, Deborah K ; Bosch, Ronald J ; Lalama, Christina M ; Cyktor, Joshua C ; Macatangay, Bernard J ; Rinaldo, Charles R ; Riddler, Sharon A ; Hogg, Evelyn ; Godfrey, Catherine ; Collier, Ann C ; Eron, Joseph J ; Mellors, John W ; ACTG A5321 Team2017 AprPLoS Pathog413
The major genetic determinants of HIV-1 control affect HLA class I peptide presentation.International HIV Controllers Study ; Pereyra, Florencia ; Jia, Xiaoming ; McLaren, Paul J ; Telenti, Amalio ; DE Bakker, Paul I W ; Walker, Bruce D ; Ripke, Stephan ; Brumme, Chanson J ; Pulit, Sara L ; Carrington, Mary ; Kadie, Carl M ; Carlson, Jonathan M ; Heckerman, David ; Graham, Robert R ; Plenge, Robert M ; Deeks, Steven G ; Giann2010 Dec 10Science6010330
No effect of raltegravir intensification on viral replication markers in the blood of HIV-1-infected patients receiving antiretroviral therapy.Gandhi, Rajesh T ; Coombs, Robert W ; Chan, Ellen S ; Bosch, Ronald J ; Zheng, Lu ; Margolis, David M ; Read, Sarah ; Kallungal, Beatrice ; Chang, Ming ; Goecker, Erin A ; Wiegand, Ann ; Kearney, Mary ; Jacobson, Jeffrey M ; D'Aquila, Richard ; Lederman, Michael M ; Mellors, John W ; Eron, Joseph J ; AIDS Clinical Trials Group (ACTG) A52442012 Mar 1J Acquir Immune Defic Syndr359
No evidence for decay of the latent reservoir in HIV-1-infected patients receiving intensive enfuvirtide-containing antiretroviral therapy.Gandhi, Rajesh T ; Bosch, Ronald J ; Aga, Evgenia ; Albrecht, Mary ; Demeter, Lisa M ; Dykes, Carrie ; Bastow, Barbara ; Para, Michael ; Lai, Jun ; Siliciano, Robert F ; Siliciano, Janet D ; Eron, Joseph J ; AIDS Clinical Trials Group A5173 Team2010 Jan 15J Infect Dis2201
Origin of Rebound Plasma HIV Includes Cells with Identical Proviruses That Are Transcriptionally Active before Stopping of Antiretroviral Therapy.Kearney, Mary F ; Wiegand, Ann ; Shao, Wei ; Coffin, John M ; Mellors, John W ; Lederman, Michael ; Gandhi, Rajesh T ; Keele, Brandon F ; Li, Jonathan Z2016 FebJ Virol390
A pilot trial of adding maraviroc to suppressive antiretroviral therapy for suboptimal CD4⁺ T-cell recovery despite sustained virologic suppression: ACTG A5256.Wilkin, Timothy J ; Lalama, Christina M ; McKinnon, John ; Gandhi, Rajesh T ; Lin, Nina ; Landay, Alan ; Ribaudo, Heather ; Fox, Lawrence ; Currier, Judith S ; Mellors, John W ; Gulick, Roy ; Tenorio, Allan R2012 Aug 15J Infect Dis4206
Predictors of residual viraemia in patients on long-term suppressive antiretroviral therapy.Zheng, Lu ; Bosch, Ronald J ; Chan, Ellen S ; Read, Sarah ; Kearney, Mary ; Margolis, David M ; Mellors, John W ; Eron, Joseph J ; Gandhi, Rajesh T ; DS Clinical Trials Group (ACTG) A5244 Team2013Antivir Ther118
Pretreatment levels of soluble cellular receptors and interleukin-6 are associated with HIV disease progression in subjects treated with highly active antiretroviral therapy.Kalayjian, Robert C ; Machekano, Rhoderick N ; Rizk, Nesrine ; Robbins, Gregory K ; Gandhi, Rajesh T ; Rodriguez, Benigno A ; Pollard, Richard B ; Lederman, Michael M ; Landay, Alan2010 Jun 15J Infect Dis12201
A randomized therapeutic vaccine trial of canarypox-HIV-pulsed dendritic cells vs. canarypox-HIV alone in HIV-1-infected patients on antiretroviral therapy.Gandhi, Rajesh T ; O'Neill, David ; Bosch, Ronald J ; Chan, Ellen S ; Bucy, R Pat ; Shopis, Janet ; Baglyos, Lynn ; Adams, Elizabeth ; Fox, Lawrence ; Purdue, Lynette ; Marshak, Ann ; Flynn, Theresa ; Masih, Reena ; Schock, Barbara ; Mildvan, Donna ; Schlesinger, Sarah J ; Marovich, Mary A ; Bhardwaj, Nina ; Jacobson, Jeffrey M ; AIDS Clin2009 Oct 9Vaccine4327
Regimen selection in the OPTIONS trial of HIV salvage therapy: drug resistance, prior therapy, and race-ethnicity determine the degree of regimen complexity.Tashima, Karen T ; Mollan, Katie R ; Na, Lumine ; Gandhi, Rajesh T ; Klingman, Karin L ; Fichtenbaum, Carl J ; Andrade, Adriana ; Johnson, Victoria A ; Eron, Joseph J ; Smeaton, Laura ; Haubrich, Richard H2015 AugHIV Clin Trials416
Replication capacity in relation to immunologic and virologic outcomes in HIV-1-infected treatment-naive subjects.Skowron, Gail ; Spritzler, John G ; Weidler, Jodi ; Robbins, Gregory K ; Johnson, Victoria A ; Chan, Ellen S ; Asmuth, David M ; Gandhi, Rajesh T ; Lie, Yolanda ; Bates, Michael ; Pollard, Richard B ; NIH/NIAID ACTG 384 Protocol Team and Monogram Biosciences2009 Mar 1J Acquir Immune Defic Syndr350
Residual plasma viraemia and infectious HIV-1 recovery from resting memory CD4 cells in patients on antiretroviral therapy: results from ACTG A5173.Gandhi, Rajesh T ; Bosch, Ronald J ; Aga, Evgenia ; Bedison, Margaret A ; Bastow, Barbara ; Schmitz, John L ; Siliciano, Janet D ; Siliciano, Robert F ; Eron, Joseph J ; Mellors, John W ; ACTG A5173 team2013Antivir Ther418
Sevelamer does not decrease lipopolysaccharide or soluble CD14 levels but decreases soluble tissue factor, low-density lipoprotein (LDL) cholesterol, and oxidized LDL cholesterol levels in individuals with untreated HIV infection.Sandler, Netanya G ; Zhang, Xinyan ; Bosch, Ronald J ; Funderburg, Nicholas T ; Choi, Andrew I ; Robinson, Janet K ; Fine, Derek M ; Coombs, Robert W ; Jacobson, Jeffrey M ; Landay, Alan L ; Douek, Daniel C ; Tressler, Randall ; Read, Sarah W ; Wilson, Cara C ; Deeks, Steven G ; Lederman, Michael M ; Gandhi, Rajesh T ; AIDS Clinical Trials2014 Nov 15J Infect Dis10210
The size of the expressed HIV reservoir predicts timing of viral rebound after treatment interruption.Li, Jonathan Z ; Etemad, Behzad ; Ahmed, Hayat ; Aga, Evgenia ; Bosch, Ronald J ; Mellors, John W ; Kuritzkes, Daniel R ; Lederman, Michael M ; Para, Michael ; Gandhi, Rajesh T2016 Jan 28AIDS330
T-cell responses targeting HIV Nef uniquely correlate with infected cell frequencies after long-term antiretroviral therapy.Thomas, Allison S ; Jones, Kimberley L ; Gandhi, Rajesh T ; McMahon, Deborah K ; Cyktor, Joshua C ; Chan, Dora ; Huang, Szu-Han ; Truong, Ronald ; Bosque, Alberto ; Macedo, Amanda B ; Kovacs, Colin ; Benko, Erika ; Eron, Joseph J ; Bosch, Ronald J ; Lalama, Christina M ; Simmens, Samuel ; Walker, Bruce D ; Mellors, John W ; Jones, R Brad2017 SepPLoS Pathog913
Transcriptional Changes in CD8(+) T Cells During Antiretroviral Therapy Intensified With Raltegravir.Ouyang, Zhengyu ; Buzon, Maria J ; Zheng, Lu ; Sun, Hong ; Yu, Xu G ; Bosch, Ronald J ; Mellors, John W ; Eron, Joseph J ; Gandhi, Rajesh T ; Lichterfeld, Mathias2015 AprOpen Forum Infect Dis22
Virologic and immunologic effects of adding maraviroc to suppressive antiretroviral therapy in individuals with suboptimal CD4+ T-cell recovery.Cillo, Anthony R ; Hilldorfer, Benedict B ; Lalama, Christina M ; McKinnon, John E ; Coombs, Robert W ; Tenorio, Allan R ; Fox, Lawrence ; Gandhi, Rajesh T ; Ribaudo, Heather ; Currier, Judith S ; Gulick, Roy M ; Wilkin, Timothy J ; Mellors, John W2015 Oct 23AIDS1629