ACTG Publications

AIDS clinical trials group longitudinal linked randomized trials (ALLRT): rationale, design, and baseline characteristics.Smurzynski, Marlene ; Collier, Ann C ; Koletar, Susan L ; Bosch, Ronald J ; Wu, Kunling ; Bastow, Barbara ; Benson, Constance A2008 Jul-AugHIV Clin Trials49
Antiretroviral therapy and efficacy after virologic failure on first-line boosted protease inhibitor regimens.Zheng, Yu ; Hughes, Michael D ; Lockman, Shahin ; Benson, Constance A ; Hosseinipour, Mina C ; Campbell, Thomas B ; Gulick, Roy M ; Daar, Eric S ; Sax, Paul E ; Riddler, Sharon A ; Haubrich, Richard ; Salata, Robert A ; Currier, Judith S2014 Sep 15Clin Infect Dis659
Atazanavir plus ritonavir or efavirenz as part of a 3-drug regimen for initial treatment of HIV-1.Daar, Eric S ; Tierney, Camlin ; Fischl, Margaret A ; Sax, Paul E ; Mollan, Katie ; Budhathoki, Chakra ; Godfrey, Catherine ; Jahed, Nasreen C ; Myers, Laurie ; Katzenstein, David ; Farajallah, Awny ; Rooney, James F ; Pappa, Keith A ; Woodward, William C ; Patterson, Kristine ; Bolivar, Hector ; Benson, Constance A ; Collier, Ann C ; AIDS2011 Apr 5Ann Intern Med7154
Drug-resistant virus has reduced ability to induce immune activation.Wang, Rui ; Bosch, Ronald J ; Benson, Constance A ; Lederman, Michael M2012 Dec 1J Acquir Immune Defic Syndr461
Efavirenz Pharmacokinetics and Pharmacodynamics in HIV-Infected Persons Receiving Rifapentine and Isoniazid for Tuberculosis Prevention.Podany, Anthony T ; Bao, Yajing ; Swindells, Susan ; Chaisson, Richard E ; Andersen, Janet W ; Mwelase, Thando ; Supparatpinyo, Khuanchai ; Mohapi, Lerato ; Gupta, Amita ; Benson, Constance A ; Kim, Peter ; Fletcher, Courtney V ; AIDS Clinical Trials Group A5279 Study Team2015 Oct 15Clin Infect Dis861
Effect of early versus deferred antiretroviral therapy for HIV on survival.Kitahata, Mari M ; Gange, Stephen J ; Abraham, Alison G ; Merriman, Barry ; Saag, Michael S ; Justice, Amy C ; Hogg, Robert S ; Deeks, Steven G ; Eron, Joseph J ; Brooks, John T ; Rourke, Sean B ; Gill, M John ; Bosch, Ronald J ; Martin, Jeffrey N ; Klein, Marina B ; Jacobson, Lisa P ; Rodriguez, Benigno ; Sterling, Timothy R ; Kirk, Grego2009 Apr 30N Engl J Med18360
Efficacy and tolerability of 3 nonnucleoside reverse transcriptase inhibitor-sparing antiretroviral regimens for treatment-naive volunteers infected with HIV-1: a randomized, controlled equivalence trial.Lennox, Jeffrey L ; Landovitz, Raphael J ; Ribaudo, Heather J ; Ofotokun, Ighovwerha ; Na, Lumine H ; Godfrey, Catherine ; Kuritzkes, Daniel R ; Sagar, Manish ; Brown, Todd T ; Cohn, Susan E ; McComsey, Grace A ; Aweeka, Francesca ; Fichtenbaum, Carl J ; Presti, Rachel M ; Koletar, Susan L ; Haas, David W ; Patterson, Kristine B ; Benson, 2014 Oct 7Ann Intern Med7161
Epidemiology of Kaposi's sarcoma-associated herpesvirus in HIV-1-infected US persons in the era of combination antiretroviral therapy.Labo, Nazzarena ; Miley, Wendell ; Benson, Constance A ; Campbell, Thomas B ; Whitby, Denise2015 Jun 19AIDS1029
Fish oil and fenofibrate for the treatment of hypertriglyceridemia in HIV-infected subjects on antiretroviral therapy: results of ACTG A5186.Gerber, John G ; Kitch, Douglas W ; Fichtenbaum, Carl J ; Zackin, Robert A ; Charles, Stéphannie ; Hogg, Evelyn ; Acosta, Edward P ; Connick, Elizabeth ; Wohl, David ; Kojic, E Milu ; Benson, Constance A ; Aberg, Judith A2008 Apr 1J Acquir Immune Defic Syndr447
Genital HIV-1 Shedding With Dolutegravir (DTG) Plus Lamivudine (3TC) Dual Therapy.Gianella, Sara ; Marconi, Vincent C ; Berzins, Baiba ; Benson, Constance A ; Sax, Paul ; Fichtenbaum, Carl J ; Wilkin, Timothy ; Vargas, Millie ; Deng, Qianqian ; Oliveira, Michelli F ; Moser, Carlee ; Taiwo, Babafemi O2018 Dec 15J Acquir Immune Defic Syndr579
Immunogenetics of CD4 lymphocyte count recovery during antiretroviral therapy: An AIDS Clinical Trials Group study.Haas, David W ; Geraghty, Daniel E ; Andersen, Janet ; Mar, Jessica ; Motsinger, Alison A ; D'Aquila, Richard T ; Unutmaz, Derya ; Benson, Constance A ; Ritchie, Marylyn D ; Landay, Alan ; AIDS Clinical Trials Group2006 Oct 15J Infect Dis8194
The impact of age on the prognostic capacity of CD8+ T-cell activation during suppressive antiretroviral therapy.Lok, Judith J ; Hunt, Peter W ; Collier, Ann C ; Benson, Constance A ; Witt, Mallory D ; Luque, Amneris E ; Deeks, Steven G ; Bosch, Ronald J2013 Aug 24AIDS1327
The Impact of Statin and Angiotensin-Converting Enzyme Inhibitor/Angiotensin Receptor Blocker Therapy on Cognitive Function in Adults With Human Immunodeficiency Virus Infection.Erlandson, Kristine M ; Kitch, Douglas ; Wester, C William ; Kalayjian, Robert C ; Overton, Edgar Turner ; Castillo-Mancilla, Jose ; Koletar, Susan L ; Benson, Constance A ; Campbell, Thomas B ; Robertson, Kevin ; Lok, Judith J2017 Nov 29Clin Infect Dis1265
Incidence of non-AIDS-defining cancer in antiretroviral treatment-naïve subjects after antiretroviral treatment initiation: an ACTG longitudinal linked randomized trials analysis.Krishnan, Supriya ; Schouten, Jeffrey T ; Jacobson, Denise L ; Benson, Constance A ; Collier, Ann C ; Koletar, Susan L ; Santana, Jorge ; Sattler, Fred R ; Mitsuyasu, Ronald ; ACTG-ALLRT Protocol Team2011Oncology1-280
Long-term increase in CD4+ T-cell counts during combination antiretroviral therapy for HIV-1 infection.Lok, Judith J ; Bosch, Ronald J ; Benson, Constance A ; Collier, Ann C ; Robbins, Gregory K ; Shafer, Robert W ; Hughes, Michael D ; ALLRT team2010 Jul 31AIDS1224
No risk of myocardial infarction associated with initial antiretroviral treatment containing abacavir: short and long-term results from ACTG A5001/ALLRT.Ribaudo, Heather J ; Benson, Constance A ; Zheng, Yu ; Koletar, Susan L ; Collier, Ann C ; Lok, Judith J ; Smurzynski, Marlene ; Bosch, Ronald J ; Bastow, Barbara ; Schouten, Jeffrey T ; ACTG A5001/ALLRT Protocol Team2011 Apr 1Clin Infect Dis752
Novel dosing strategies increase exposures of the potent antituberculosis drug rifapentine but are poorly tolerated in healthy volunteers.Dooley, Kelly E ; Savic, Radojka M ; Park, Jeong-Gun ; Cramer, Yoninah ; Hafner, Richard ; Hogg, Evelyn ; Janik, Jennifer ; Marzinke, Mark A ; Patterson, Kristine ; Benson, Constance A ; Hovind, Laura ; Dorman, Susan E ; Haas, David W ; ACTG A5311 Study Team2015Antimicrob Agents Chemother659
Pretreatment factors associated with 3-year (144-week) virologic and immunologic responses to potent antiretroviral therapy.Bosch, Ronald J ; Bennett, Kara ; Collier, Ann C ; Zackin, Robert ; Benson, Constance A2007 Mar 1J Acquir Immune Defic Syndr344
A randomized trial of treatment interruption before optimized antiretroviral therapy for persons with drug-resistant HIV: 48-week virologic results of ACTG A5086.Benson, Constance A ; Vaida, Florin ; Havlir, Diane V ; Downey, Gerald F ; Lederman, Michael M ; Gulick, Roy M ; Glesby, Marshall J ; Wantman, Michael ; Bixby, Christian J ; Rinehart, Alex R ; Snyder, Sally ; Wang, Rui ; Patel, Sheran ; Mellors, John W ; ACTG A5086 Study Team2006 Nov 1J Infect Dis9194
Regulatory T cells and the risk of CMV end-organ disease in patients with AIDS.Weinberg, Adriana ; Bosch, Ronald ; Bennett, Kara ; Tovar-Salazar, Adriana ; Benson, Constance A ; Collier, Ann C ; Zolopa, Andrew ; Gulick, Roy M ; Wohl, David ; Polsky, Bruce ; Erice, Alejo ; Jacobson, Mark A2014 May 1J Acquir Immune Defic Syndr166
Relationship between CD4+ T-cell counts/HIV-1 RNA plasma viral load and AIDS-defining events among persons followed in the ACTG longitudinal linked randomized trials study.Smurzynski, Marlene ; Wu, Kunling ; Benson, Constance A ; Bosch, Ronald J ; Collier, Ann C ; Koletar, Susan L2010 SepJ Acquir Immune Defic Syndr155
Relationship between weight, efavirenz exposure, and virologic suppression in HIV-infected patients on rifampin-based tuberculosis treatment in the AIDS Clinical Trials Group A5221 STRIDE Study.Luetkemeyer, Anne F ; Rosenkranz, Susan L ; Lu, Darlene ; Marzan, Florence ; Ive, Prudence ; Hogg, Evelyn ; Swindells, Susan ; Benson, Constance A ; Grinsztejn, Beatriz ; Sanne, Ian M ; Havlir, Diane V ; Aweeka, Francesca ; Adult AIDS Clinical Trials Group A5221 Study Team2013 AugClin Infect Dis457
Safety and Immunogenicity of Zoster Vaccine Live in Human Immunodeficiency Virus-Infected Adults With CD4+ Cell Counts >200 Cells/mL Virologically Suppressed on Antiretroviral Therapy.Benson, Constance A ; Andersen, Janet W ; Macatangay, Bernard J C ; Mailliard, Robbie B ; Rinaldo, Charles R ; Read, Sarah ; Bozzolo, Dawn R ; Purdue, Lynette ; Jennings, Cheryl ; Keefer, Michael C ; Glesby, Marshall ; Tebas, Pablo ; Russell, Amy Falk ; Martin, Jason ; Annunziato, Paula ; Popmihajlov, Zoran ; Lennox, Jeffrey L2018 Nov 13Clin Infect Dis1167
Testosterone supplementation of megestrol therapy does not enhance lean tissue accrual in men with human immunodeficiency virus-associated weight loss: a randomized, double-blind, placebo-controlled, multicenter trial.Mulligan, Kathleen ; Zackin, Robert ; Von Roenn, Jamie H ; Chesney, Margaret A ; Egorin, Merrill J ; Sattler, Fred R ; Benson, Constance A ; Liu, Tun ; Umbleja, Triin ; Shriver, Sharon ; Auchus, Richard J ; Schambelan, Morris ; ACTG 313 Study Team2007 FebJ Clin Endocrinol Metab292
Three months of weekly rifapentine and isoniazid for treatment of Mycobacterium tuberculosis infection in HIV-coinfected persons.Sterling, Timothy R ; Scott, Nigel A ; Miro, José M ; Calvet, Guilherme ; La Rosa, Alberto ; Infante, Rosa ; Chen, Michael P ; Benator, Debra A ; Gordin, Fred ; Benson, Constance A ; Chaisson, Richard E ; Villarino, M Elsa ; Tuberculosis Trials Consortium, the AIDS Clinical Trials Group for the PREVENT TB Trial (TBTC Study 26ACTG 5259) The2016 Jun 19AIDS1030
Trends in multidrug treatment failure and subsequent mortality among antiretroviral therapy-experienced patients with HIV infection in North America.Deeks, Steven G ; Gange, Stephen J ; Kitahata, Mari M ; Saag, Michael S ; Justice, Amy C ; Hogg, Robert S ; Eron, Joseph J ; Brooks, John T ; Rourke, Sean B ; Gill, M John ; Bosch, Ronald J ; Benson, Constance A ; Collier, Ann C ; Martin, Jeffrey N ; Klein, Marina B ; Jacobson, Lisa P ; Rodriguez, Benigno ; Sterling, Timothy R ; Kirk, Greg2009 Nov 15Clin Infect Dis1049
Tuberculosis immune reconstitution inflammatory syndrome in A5221 STRIDE: timing, severity, and implications for HIV-TB programs.Luetkemeyer, Anne F ; Kendall, Michelle A ; Nyirenda, Mulinda ; Wu, Xingye ; Ive, Prudence ; Benson, Constance A ; Andersen, Janet W ; Swindells, Susan ; Sanne, Ian M ; Havlir, Diane V ; Kumwenda, Johnstone ; Adult AIDS Clinical Trials Group A5221 Study Team2014 Apr 1J Acquir Immune Defic Syndr465