ACTG Publications

Age-related changes in plasma concentrations of the HIV protease inhibitor lopinavir.Crawford, Keith W ; Spritzler, John ; Kalayjian, Robert C ; Parsons, Teresa ; Landay, Alan ; Pollard, Richard ; Stocker, Vicki ; Lederman, Michael M ; Flexner, Charles ; AIDS Clinical Trials Protocol 5015 Team2010 JunAIDS Res Hum Retroviruses626
Biomarkers Associated with Death After Initiating Treatment for Tuberculosis and HIV in Patients with Very Low CD Cells.Sattler, Fred R ; Chelliah, Daniel ; Wu, Xingye ; Sanchez, Alejandro ; Kendall, Michelle A ; Hogg, Evelyn ; Lagat, David ; Lalloo, Umesh ; Veloso, Valdilea ; Havlir, Diane V ; Landay, Alan2018Pathog Immun13
CD28-negative CD4+ and CD8+ T cells in antiretroviral therapy-naive HIV-infected adults enrolled in adult clinical trials group studies.Tassiopoulos, Katherine ; Landay, Alan ; Collier, Ann C ; Connick, Elizabeth ; Deeks, Steven G ; Hunt, Peter ; Lewis, Dorothy E ; Wilson, Cara ; Bosch, Ronald2012 JunJ Infect Dis11205
Continuing or adding IL-2 in patients treated with antiretroviral therapy (ACTG Protocol A5051, a rollover trial of ACTG Protocol A328).Bosch, Ronald J ; Pollard, Richard B ; Landay, Alan ; Aga, Evgenia ; Fox, Lawrence ; Mitsuyasu, Ronald2010AIDS Res Ther7
Determinants of CD4+ T cell recovery during suppressive antiretroviral therapy: association of immune activation, T cell maturation markers, and cellular HIV-1 DNA.Goicoechea, Miguel ; Smith, Davey M ; Liu, Lin ; May, Susanne ; Tenorio, Allan R ; Ignacio, Caroline C ; Landay, Alan ; Haubrich, Richard2006 Jul 1J Infect Dis1194
GBV-C viremia is associated with reduced CD4 expansion in HIV-infected people receiving HAART and interleukin-2 therapy.Stapleton, Jack T ; Chaloner, Kathryn ; Zhang, Jingyang ; Klinzman, Donna ; Souza, Inara E ; Xiang, Jinhua ; Landay, Alan ; Fahey, John ; Pollard, Richard ; Mitsuyasu, Ronald2009 Mar 13AIDS523
Immunogenetics of CD4 lymphocyte count recovery during antiretroviral therapy: An AIDS Clinical Trials Group study.Haas, David W ; Geraghty, Daniel E ; Andersen, Janet ; Mar, Jessica ; Motsinger, Alison A ; D'Aquila, Richard T ; Unutmaz, Derya ; Benson, Constance A ; Ritchie, Marylyn D ; Landay, Alan ; AIDS Clinical Trials Group2006 Oct 15J Infect Dis8194
Interferon-alpha administration enhances CD8+ T cell activation in HIV infection.Manion, Maura ; Rodriguez, Benigno ; Medvik, Kathleen ; Hardy, Gareth ; Harding, Clifford V ; Schooley, Robert T ; Pollard, Richard ; Asmuth, David ; Murphy, Robert ; Barker, Edward ; Brady, Kirsten E ; Landay, Alan ; Funderburg, Nick ; Sieg, Scott F ; Lederman, Michael M2012PLoS One17
Intracellular Casp8p41 content is inversely associated with CD4 T cell count.Cummins, Nathan W ; Jiang, Wei ; McGinty, John ; Bren, Gary D ; Bosch, Ronald J ; Landay, Alan ; Deeks, Steven G ; Martin, Jeffrey N ; Douek, Daniel ; Lederman, Michael M ; Brenchley, Jason ; Badley, Andrew D2010 Aug 15J Infect Dis3202
Less Bone Loss With Maraviroc- Versus Tenofovir-Containing Antiretroviral Therapy in the AIDS Clinical Trials Group A5303 Study.Taiwo, Babafemi O ; Chan, Ellen S ; Fichtenbaum, Carl J ; Ribaudo, Heather ; Tsibris, Athe ; Klingman, Karin L ; Eron, Joseph J ; Berzins, Baiba ; Robertson, Kevin ; Landay, Alan ; Ofotokun, Igho ; Brown, Todd ; AIDS Clinical Trials Group A5303 Study Team2015 Oct 1Clin Infect Dis761
Microbial translocation is a cause of systemic immune activation in chronic HIV infection.Brenchley, Jason M ; Price, David A ; Schacker, Timothy W ; Asher, Tedi E ; Silvestri, Guido ; Rao, Srinivas ; Kazzaz, Zachary ; Bornstein, Ethan ; Lambotte, Olivier ; Altmann, Daniel ; Blazar, Bruce R ; Rodriguez, Benigno ; Teixeira-Johnson, Leia ; Landay, Alan ; Martin, Jeffrey N ; Hecht, Frederick M ; Picker, Louis J ; Lederman, Michael2006 DecNat Med1212
Older age is associated with peripheral blood expansion of naïve B cells in HIV-infected subjects on antiretroviral therapy.Van Epps, Puja ; Matining, Roy M ; Tassiopoulos, Katherine ; Anthony, Donald D ; Landay, Alan ; Kalayjian, Robert C ; Canaday, David H2014PLoS One99
Older HIV-infected patients on antiretroviral therapy have B-cell expansion and attenuated CD4 cell increases with immune activation reduction.Kalayjian, Robert C ; Spritzler, John ; Matining, Roy M ; Fiscus, Susan A ; Gross, Barry H ; Francis, Isaac R ; Pollard, Richard B ; Lederman, Michael M ; Landay, Alan2013 Jun 19AIDS1027
A pilot trial of adding maraviroc to suppressive antiretroviral therapy for suboptimal CD4⁺ T-cell recovery despite sustained virologic suppression: ACTG A5256.Wilkin, Timothy J ; Lalama, Christina M ; McKinnon, John ; Gandhi, Rajesh T ; Lin, Nina ; Landay, Alan ; Ribaudo, Heather ; Fox, Lawrence ; Currier, Judith S ; Mellors, John W ; Gulick, Roy ; Tenorio, Allan R2012 Aug 15J Infect Dis4206
Plasma levels of bacterial DNA correlate with immune activation and the magnitude of immune restoration in persons with antiretroviral-treated HIV infection.Jiang, Wei ; Lederman, Michael M ; Hunt, Peter ; Sieg, Scott F ; Haley, Kathryn ; Rodriguez, Benigno ; Landay, Alan ; Martin, Jeffrey ; Sinclair, Elizabeth ; Asher, Ava I ; Deeks, Steven G ; Douek, Daniel C ; Brenchley, Jason M2009 Apr 15J Infect Dis8199
Pretreatment levels of soluble cellular receptors and interleukin-6 are associated with HIV disease progression in subjects treated with highly active antiretroviral therapy.Kalayjian, Robert C ; Machekano, Rhoderick N ; Rizk, Nesrine ; Robbins, Gregory K ; Gandhi, Rajesh T ; Rodriguez, Benigno A ; Pollard, Richard B ; Lederman, Michael M ; Landay, Alan2010 Jun 15J Infect Dis12201
A Randomized, Double-Blinded, Placebo-Controlled Trial of Sitagliptin for Reducing Inflammation and Immune Activation in Treated and Suppressed HIV Infection.Dubé, Michael P ; Chan, Ellen S ; Lake, Jordan E ; Williams, Brett ; Kinslow, Jennifer ; Landay, Alan ; Coombs, Robert W ; Floris-Moore, Michelle ; Ribaudo, Heather J ; Yarasheski, Kevin E ; ACTG 5346 Team2018 Dec 10Clin Infect Dis
A randomized study of antiviral medication switch at lower- versus higher-switch thresholds: AIDS Clinical Trials Group Study A5115.Riddler, Sharon A ; Jiang, Hongyu ; Tenorio, Allan ; Huang, Hairong ; Kuritzkes, Daniel R ; Acosta, Edward P ; Landay, Alan ; Bastow, Barbara ; Haas, David W ; Tashima, Karen T ; Jain, Mamta K ; Deeks, Steven G ; Bartlett, John A2007Antivir Ther412
A randomized trial of interleukin-2 during withdrawal of antiretroviral treatment.Bosch, Ronald J ; Pollard, Richard B ; Landay, Alan ; Aga, Evgenia ; Fox, Lawrence ; Mitsuyasu, Ronald ; AIDS Clinical Trials Group A5132 Team2011 JunJ Interferon Cytokine Res631
Soluble Urokinase Plasminogen Activator Receptor (suPAR) is predictive of Non-AIDS Events during Antiretroviral Therapy-mediated Viral Suppression.Hoenigl, Martin ; Moser, Carlee ; Funderburg, Nicholas ; Bosch, Ronald ; Kantor, Amy ; Zhang, Yonglong ; Eugen-Olsen, Jesper ; Finkelman, Malcolm ; Reiser, Jochen ; Landay, Alan ; Moisi, Daniela ; Lederman, Michael M ; Gianella, Sara ; ACTG NWCS 411 study team2018 Nov 12Clin Infect Dis
The virologic, immunologic, and clinical effects of interleukin 2 with potent antiretroviral therapy in patients with moderately advanced human immunodeficiency virus infection: a randomized controlled clinical trial--AIDS Clinical Trials Group 328.Mitsuyasu, Ronald ; Gelman, Rebecca ; Cherng, Deborah Weng ; Landay, Alan ; Fahey, John ; Reichman, Richard ; Erice, Alejo ; Bucy, R Pat ; Kilby, J Michael ; Lederman, Michael M ; Hamilton, Carol D ; Lertora, Juan ; White, Becky L ; Tebas, Pablo ; Duliege, Anne-Marie ; Pollard, Richard B ; AIDS Clinical Trials Group 328 Study Team2007 Mar 26Arch Intern Med6167