ACTG Publications

TitleAuthorsDateJournalIssueVolume
Impact of Larger Sputum Volume on XpertMTB/RIF Assay Detection of Mycobacterium tuberculosis in Smear-Negative Individuals with Suspected Tuberculosis.Badal-Faesen, Sharlaa ; Firnhaber, Cynthia ; Kendall, Michelle A ; Wu, Xingye ; Grinsztejn, Beatriz ; Escada, Rodrigo Otavio da Silva ; Fernandez, Michel ; Hogg, Evelyn ; Sanne, Ian ; Johnson, Pamela ; Alland, David ; Mazurek, Gerald H ; Benator, Debra A ; Luetkemeyer, Anne F ; AIDS Clinical Trials Group A5295 ; Tuberculosis Trials Consort2017 Aug 07J Clin Med86
Effect of hydroxyurea and dideoxyinosine on intracellular 3'-deoxyadenosine-5'-triphosphate concentrations in HIV-infected patients.Bakshi, Rahul P ; Hamzeh, Fayez ; Frank, Ian ; Eron, Joseph J ; Bosch, Ronald J ; Rosenkranz, Susan L ; Cramer, Yoninah S ; Ussery, Michael ; Flexner, Charles2007 NovAIDS Res Hum Retroviruses1123
Pre-cART Elevation of CRP and CD4+ T-Cell Immune Activation Associated With HIV Clinical Progression in a Multinational Case-Cohort Study.Balagopal, Ashwin ; Asmuth, David M ; Yang, Wei-Teng ; Campbell, Thomas B ; Gupte, Nikhil ; Smeaton, Laura ; Kanyama, Cecilia ; Grinsztejn, Beatriz ; Santos, Breno ; Supparatpinyo, Khuanchai ; Badal-Faesen, Sharlaa ; Lama, Javier R ; Lalloo, Umesh G ; Zulu, Fatima ; Pawar, Jyoti S ; Riviere, Cynthia ; Kumarasamy, Nagalingeswaran ; Hakim, J2015 Oct 1J Acquir Immune Defic Syndr270
Continued Elevation of Interleukin-18 and Interferon-γ After Initiation of Antiretroviral Therapy and Clinical Failure in a Diverse Multicountry Human Immunodeficiency Virus Cohort.Balagopal, Ashwin ; Gupte, Nikhil ; Shivakoti, Rupak ; Cox, Andrea L ; Yang, Wei-Teng ; Berendes, Sima ; Mwelase, Noluthando ; Kanyama, Cecilia ; Pillay, Sandy ; Samaneka, Wadzanai ; Santos, Breno ; Poongulali, Selvamuthu ; Tripathy, Srikanth ; Riviere, Cynthia ; Lama, Javier R ; Cardoso, Sandra W ; Sugandhavesa, Patcharaphan ; Semba, Rich2016 SepOpen Forum Infect Dis33
Effect of HIV Antibody VRC01 on Viral Rebound after Treatment Interruption.Bar, Katharine J ; Sneller, Michael C ; Harrison, Linda J ; Justement, J Shawn ; Overton, Edgar T ; Petrone, Mary E ; Salantes, D Brenda ; Seamon, Catherine A ; Scheinfeld, Benjamin ; Kwan, Richard W ; Learn, Gerald H ; Proschan, Michael A ; Kreider, Edward F ; Blazkova, Jana ; Bardsley, Mark ; Refsland, Eric W ; Messer, Michael ; Clarridg2016 11 24N Engl J Med21375
HIV-Infected Women Gain More Weight than HIV-Infected Men Following the Initiation of Antiretroviral Therapy.Bares, Sara H ; Smeaton, Laura M ; Xu, Ai ; Godfrey, Catherine ; McComsey, Grace A2018 09J Womens Health (Larchmt)927
A genome-to-genome analysis of associations between human genetic variation, HIV-1 sequence diversity, and viral control.Bartha, István ; Carlson, Jonathan M ; Brumme, Chanson J ; McLaren, Paul J ; Brumme, Zabrina L ; John, Mina ; Haas, David W ; Martinez-Picado, Javier ; Dalmau, Judith ; López-Galíndez, Cecilio ; Casado, Concepción ; Rauch, Andri ; Günthard, Huldrych F ; Bernasconi, Enos ; Vernazza, Pietro ; Klimkait, Thomas ; Yerly, Sabine ; O'Brien, Steph2013Elife2
Comparative efficacy of nucleoside/nucleotide reverse transcriptase inhibitors in combination with efavirenz: results of a systematic overview.Bartlett, John A ; Chen, Shan-Shan ; Quinn, Joseph B2007 Jul-AugHIV Clin Trials48
Lopinavir/ritonavir monotherapy after virologic failure of first-line antiretroviral therapy in resource-limited settings.Bartlett, John A ; Ribaudo, Heather J ; Wallis, Carole L ; Aga, Evgenia ; Katzenstein, David A ; Stevens, Wendy S ; Norton, Michael R ; Klingman, Karin L ; Hosseinipour, Mina C ; Crump, John A ; Supparatpinyo, Khuanchai ; Badal-Faesen, Sharlaa ; Kallungal, Beatrice A ; Kumarasamy, Nagalingeswaran2012 Jul 17AIDS1126
Effect of HIV-1 infection on human DNA yield from saliva.Basham, Rebecca J ; Richardson, Danielle M ; Sutcliffe, Cara B ; Haas, David W2009 Jul-AugHIV Clin Trials410
Effects of Pegylated Interferon/Ribavirin on Bone Turnover Markers in HIV/Hepatitis C Virus-Coinfected Patients.Bedimo, Roger ; Kang, Minhee ; Tebas, Pablo ; Overton, Edgar T ; Hollabaugh, Kimberly ; McComsey, Grace ; Bhattacharya, Debika ; Evans, Christopher ; Brown, Todd T ; Taiwo, Babafemi2016 AprAIDS Res Hum Retroviruses432
Diversity and Tropism of HIV-1 Rebound Virus Populations in Plasma Level After Treatment Discontinuation.Bednar, Maria M ; Hauser, Blake M ; Zhou, Shuntai ; Jacobson, Jeffrey M ; Eron, Joseph J ; Frank, Ian ; Swanstrom, Ronald2016 Aug 01J Infect Dis3214
Recent advances in management of the HIV/HCV coinfected patient.Bednasz, Cindy J ; Sawyer, Joshua R ; Martinez, Anthony ; Rose, Patrick G ; Sithole, Samantha S ; Hamilton, Holly R ; Kaufman, Farzia S ; Venuto, Charles S ; Ma, Qing ; Talal, Andrew ; Morse, Gene D2015Future Virol810
Efavirenz Therapeutic Range in HIV-1 Treatment-Naive Participants.Bednasz, Cindy J ; Venuto, Charles S ; Ma, Qing ; Daar, Eric S ; Sax, Paul E ; Fischl, Margaret A ; Collier, Ann C ; Smith, Kimberly Y ; Tierney, Camlin ; Yang, Yang ; Wilding, Gregory E ; Morse, Gene D2017 DecTher Drug Monit639
Hematologic toxicity associated with interferon-based hepatitis C therapy in HIV type 1-coinfected subjects.Behler, Caroline M ; Vittinghoff, Eric ; Lin, Feng ; Chung, Raymond T ; Peters, Marion G ; Robbins, Gregory K ; Volberding, Paul A2007 May 15Clin Infect Dis1044
Safety and Immunogenicity of Zoster Vaccine Live in Human Immunodeficiency Virus-Infected Adults With CD4+ Cell Counts >200 Cells/mL Virologically Suppressed on Antiretroviral Therapy.Benson, Constance A ; Andersen, Janet W ; Macatangay, Bernard J C ; Mailliard, Robbie B ; Rinaldo, Charles R ; Read, Sarah ; Bozzolo, Dawn R ; Purdue, Lynette ; Jennings, Cheryl ; Keefer, Michael C ; Glesby, Marshall ; Tebas, Pablo ; Russell, Amy Falk ; Martin, Jason ; Annunziato, Paula ; Popmihajlov, Zoran ; Lennox, Jeffrey L2018 Nov 13Clin Infect Dis1167
A randomized trial of treatment interruption before optimized antiretroviral therapy for persons with drug-resistant HIV: 48-week virologic results of ACTG A5086.Benson, Constance A ; Vaida, Florin ; Havlir, Diane V ; Downey, Gerald F ; Lederman, Michael M ; Gulick, Roy M ; Glesby, Marshall J ; Wantman, Michael ; Bixby, Christian J ; Rinehart, Alex R ; Snyder, Sally ; Wang, Rui ; Patel, Sheran ; Mellors, John W ; ACTG A5086 Study Team2006 Nov 1J Infect Dis9194
HIV-1 DNA decay dynamics in blood during more than a decade of suppressive antiretroviral therapy.Besson, Guillaume J ; Lalama, Christina M ; Bosch, Ronald J ; Gandhi, Rajesh T ; Bedison, Margaret A ; Aga, Evgenia ; Riddler, Sharon A ; McMahon, Deborah K ; Hong, Feiyu ; Mellors, John W2014 Nov 1Clin Infect Dis959
Changes in abdominal fat following antiretroviral therapy initiation in HIV-infected individuals correlate with waist circumference and self-reported changes.Bhagwat, Priya ; Ofotokun, Ighovwerha ; McComsey, Grace A ; Brown, Todd T ; Moser, Carlee ; Sugar, Catherine A ; Currier, Judith S2017Antivir Ther722
Effects of testosterone supplementation on whole body and regional fat mass and distribution in human immunodeficiency virus-infected men with abdominal obesity.Bhasin, Shalender ; Parker, Robert A ; Sattler, Fred ; Haubrich, Richard ; Alston, Beverly ; Umbleja, Triin ; Shikuma, Cecilia M ; AIDS Clinical Trials Group Protocol A5079 Study Team2007 MarJ Clin Endocrinol Metab392
Risk factors for early mortality on antiretroviral therapy in advanced HIV-infected adults.Bisson, Gregory P ; Ramchandani, Ritesh ; Miyahara, Sachiko ; Mngqibisa, Rosie ; Matoga, Mitch ; Ngongondo, McNeil ; Samaneka, Wadzanai ; Koech, Lucy ; Naidoo, Kogieleum ; Rassool, Mohammed ; Kirui, Fredrick ; Banda, Peter ; Mave, Vidya ; Kadam, Dileep ; Leger, Paul ; Henestroza, German ; Manabe, Yukari C ; Bao, Jing ; Kumwenda, Johnstone 2017 Oct 23AIDS1631
Effects of HCV treatment on cytokine expression during HCV/HIV coinfection.Blackard, Jason T ; Kang, Minhee ; Sherman, Kenneth E ; Koziel, Margaret James ; Peters, Marion G ; Chung, Raymond T2006 NovJ Interferon Cytokine Res1126
Viral factors associated with cytokine expression during HCV/HIV co-infection.Blackard, Jason T ; Kang, Minhee ; St Clair, J Benjamin ; Lin, Wenyu ; Kamegaya, Yoshitaka ; Sherman, Kenneth E ; Koziel, Margaret James ; Peters, Marion G ; Andersen, Janet ; Chung, Raymond T ; Aids Clinical Trials Group A5071 Study Team2007 AprJ Interferon Cytokine Res427
Examining the challenges and solutions to the implementation of trials in resource-limited settings: Limited Resource Trials.Blanchard-Horan, Christina ; Stocker, Vicki ; Moran, Laura ; Ferguson, Elaine Okubo ; Klingman, Karin L ; McMahon, Deborah ; Hitti, Jane2012 Jan 1Appl Clin Trials121
Relationship between microbial translocation and endothelial function in HIV infected patients.Blodget, Emily ; Shen, Changyu ; Aldrovandi, Grace ; Rollie, Adrienne ; Gupta, Samir K ; Stein, James H ; Dubé, Michael P2012PLoS One87
Low-frequency nevirapine (NVP)-resistant HIV-1 variants are not associated with failure of antiretroviral therapy in women without prior exposure to single-dose NVP.Boltz, Valerie F ; Bao, Yajing ; Lockman, Shahin ; Halvas, Elias K ; Kearney, Mary F ; McIntyre, James A ; Schooley, Robert T ; Hughes, Michael D ; Coffin, John M ; Mellors, John W ; OCTANE/A5208 Team2014 Mar 1J Infect Dis5209
Role of low-frequency HIV-1 variants in failure of nevirapine-containing antiviral therapy in women previously exposed to single-dose nevirapine.Boltz, Valerie F ; Zheng, Yu ; Lockman, Shahin ; Hong, Feiyu ; Halvas, Elias K ; McIntyre, James ; Currier, Judith S ; Chibowa, Margret C ; Kanyama, Cecelia ; Nair, Apsara ; Owino-Ong'or, Willis ; Hughes, Michael ; Coffin, John M ; Mellors, John W2011 May 31Proc Natl Acad Sci U S A22108
Pretreatment factors associated with 3-year (144-week) virologic and immunologic responses to potent antiretroviral therapy.Bosch, Ronald J ; Bennett, Kara ; Collier, Ann C ; Zackin, Robert ; Benson, Constance A2007 Mar 1J Acquir Immune Defic Syndr344
Continuing or adding IL-2 in patients treated with antiretroviral therapy (ACTG Protocol A5051, a rollover trial of ACTG Protocol A328).Bosch, Ronald J ; Pollard, Richard B ; Landay, Alan ; Aga, Evgenia ; Fox, Lawrence ; Mitsuyasu, Ronald2010AIDS Res Ther7
A randomized trial of interleukin-2 during withdrawal of antiretroviral treatment.Bosch, Ronald J ; Pollard, Richard B ; Landay, Alan ; Aga, Evgenia ; Fox, Lawrence ; Mitsuyasu, Ronald ; AIDS Clinical Trials Group A5132 Team2011 JunJ Interferon Cytokine Res631
Changes in the slope of the CD4 cell count increase after initiation of potent antiretroviral treatment.Bosch, Ronald J ; Wang, Rui ; Vaida, Florin ; Lederman, Michael M ; Albrecht, Mary A2006 Dec 1J Acquir Immune Defic Syndr443
Loss of circulating CD4 T cells with B cell helper function during chronic HIV infection.Boswell, Kristin L ; Paris, Robert ; Boritz, Eli ; Ambrozak, David ; Yamamoto, Takuya ; Darko, Sam ; Wloka, Kaska ; Wheatley, Adam ; Narpala, Sandeep ; McDermott, Adrian ; Roederer, Mario ; Haubrich, Richard ; Connors, Mark ; Ake, Julie ; Douek, Daniel C ; Kim, Jerome ; Petrovas, Constantinos ; Koup, Richard A2014 JanPLoS Pathog110
In HIV/hepatitis C virus co-infected patients, higher 25-hydroxyvitamin D concentrations were not related to hepatitis C virus treatment responses but were associated with ritonavir use.Branch, Andrea D ; Kang, Minhee ; Hollabaugh, Kimberly ; Wyatt, Christina M ; Chung, Raymond T ; Glesby, Marshall J2013 AugAm J Clin Nutr298
Failure of initial therapy with two nucleosides and efavirenz is not associated with early emergence of mutations in the C-terminus of HIV-1 reverse transcriptase.Brehm, Jessica H ; Lalama, Christina M ; Hughes, Michael D ; Haubrich, Richard ; Riddler, Sharon A ; Sluis-Cremer, Nicolas ; Mellors, John W ; AIDS Clinical Trials Group Study A5142 Protocol Team2011 AprJ Acquir Immune Defic Syndr456
Zidovudine (AZT) monotherapy selects for the A360V mutation in the connection domain of HIV-1 reverse transcriptase.Brehm, Jessica H ; Scott, Yanille ; Koontz, Dianna L ; Perry, Steven ; Hammer, Scott ; Katzenstein, David ; Mellors, John W ; Sluis-Cremer, Nicolas ; AIDS Clinical Trials Group Study 175 Protocol Team2012PLoS One27
Microbial translocation is a cause of systemic immune activation in chronic HIV infection.Brenchley, Jason M ; Price, David A ; Schacker, Timothy W ; Asher, Tedi E ; Silvestri, Guido ; Rao, Srinivas ; Kazzaz, Zachary ; Bornstein, Ethan ; Lambotte, Olivier ; Altmann, Daniel ; Blazar, Bruce R ; Rodriguez, Benigno ; Teixeira-Johnson, Leia ; Landay, Alan ; Martin, Jeffrey N ; Hecht, Frederick M ; Picker, Louis J ; Lederman, Michael2006 DecNat Med1212
HIV escape mutations occur preferentially at HLA-binding sites of CD8 T-cell epitopes.Bronke, Corine ; Almeida, Coral-Ann M ; McKinnon, Elizabeth ; Roberts, Steven G ; Keane, Niamh M ; Chopra, Abha ; Carlson, Jonathan M ; Heckerman, David ; Mallal, Simon ; John, Mina2013 Mar 27AIDS627
Body composition, soluble markers of inflammation, and bone mineral density in antiretroviral therapy-naive HIV-1-infected individuals.Brown, Todd T ; Chen, Yun ; Currier, Judith S ; Ribaudo, Heather J ; Rothenberg, Jennifer ; Dubé, Michael P ; Murphy, Robert ; Stein, James H ; McComsey, Grace A2013 Jul 1J Acquir Immune Defic Syndr363
Osteopenia and osteoporosis in patients with HIV: a review of current concepts.Brown, Todd T ; McComsey, Grace A2006 MarCurr Infect Dis Rep28
Changes in Bone Mineral Density After Initiation of Antiretroviral Treatment With Tenofovir Disoproxil Fumarate/Emtricitabine Plus Atazanavir/Ritonavir, Darunavir/Ritonavir, or Raltegravir.Brown, Todd T ; Moser, Carlee ; Currier, Judith S ; Ribaudo, Heather J ; Rothenberg, Jennifer ; Kelesidis, Theodoros ; Yang, Otto ; Dubé, Michael P ; Murphy, Robert L ; Stein, James H ; McComsey, Grace A2015 Oct 15J Infect Dis8212
Statin therapy and changes in hip circumference among HIV-infected participants in the ALLRT Cohort.Brown, Todd T ; Smurzynski, Marlene ; Wu, Kunling ; Bosch, Ronald J ; McComsey, Grace A2009Antivir Ther614
Association between systemic inflammation and incident diabetes in HIV-infected patients after initiation of antiretroviral therapy.Brown, Todd T ; Tassiopoulos, Katherine ; Bosch, Ronald J ; Shikuma, Cecilia ; McComsey, Grace A2010 OctDiabetes Care1033
Plasma apolipoprotein L1 levels do not correlate with CKD.Bruggeman, Leslie A ; O'Toole, John F ; Ross, Michael D ; Madhavan, Sethu M ; Smurzynski, Marlene ; Wu, Kunling ; Bosch, Ronald J ; Gupta, Samir ; Pollak, Martin R ; Sedor, John R ; Kalayjian, Robert C2014 MarJ Am Soc Nephrol325
Serosorting can potentially increase HIV transmissions.Butler, David M ; Smith, Davey M2007 May 31AIDS921
The incidence, predictors and management of anaemia and its association with virological response in HCV / HIV coinfected persons treated with long-term pegylated interferon alfa 2a and ribavirin.Butt, A A ; Umbleja, T ; Andersen, J W ; Chung, R T ; Sherman, K E ; Actg A5178 Study Team2011 JunAliment Pharmacol Ther1133
Impact of peginterferon alpha and ribavirin treatment on lipid profiles and insulin resistance in Hepatitis C virus/HIV-coinfected persons: the AIDS Clinical Trials Group A5178 Study.Butt, Adeel A ; Umbleja, Triin ; Andersen, Janet W ; Sherman, Kenneth E ; Chung, Raymond T ; Actg A5178 Study Team2012 SepClin Infect Dis555