Laboratory Steering Committee

The Laboratory Steering Committee facilitates the fiscal and technical management and operations of the ACTG NL structure in support of the overall ACTG scientific research agenda and the specific agenda of the ACTG Specialty Laboratories.

The Laboratory Steering Committee is comprised of the ACTG Network Laboratory PI (Chair), ACTG NL leadership representation from core laboratories and other relevant committee representation (LTC Chair, LES, DAIDS, HDR, FSTRF, SDAC, and ACTG Operations Representation)

Laboratory Technologist Committee

The mission of the LTC is to provide input for the standardization of laboratory related logistical processes and to ensure the successful implementation and completion of ACTG/IMPAACT scientific endeavors. The mission is accomplished by:

  • Collaborating with ACTG and IMPAACT leadership, scientific committees, site management committees, and individual protocol teams in the laboratory aspects of protocols, including communication, management, and collection and processing of specimens and related data;
  • Serving as a resource to the NIAID/Division of AIDS, Statistical and Data Analysis Center (SDAC), Data Management Center (DMC), network operations centers, and clinical site monitoring group;
  • Acting as a liaison between site personnel, laboratories, clinics, the leadership of the ACTG/IMPAACT and its contractors, as well as facilitating communication and networking among the laboratories, clinics and Data Management Center;
  • Providing information and education for laboratory personnel in the areas of protocol implementation, collection and regular export of quality data, regulatory requirements, new procedures and policies;
  • Promoting uniform handling, processing, labeling, storage, and tracking of specimens (according to consensus procedures) across all clinical sites and laboratories;
  • Providing input and expertise for the development of consensus procedures;
  • Maintaining a regularly updated laboratory manual of consensus procedures that is readily available for access by all ACTG/IMPAACT laboratories.

Repository Advisory Group

The Repository Advisory Group (RAG) oversees, monitors, and implements the ACTG’s policy on the tracking, storage, disposal, and use of ACTG clinical specimens to ensure that they are consistent with the guidelines of the Office for Human Research Protections (OHRP) and the Division of AIDS.

Membership includes the ACTG and IMPAACT laboratory PIs, and representatives from both repositories, FSTRF, the ISLs, the VSLs, LTC, and the network operations centers.