Clinical utility of HIV standard genotyping among antiretroviral-naive individuals with unknown duration of infection.

TitleClinical utility of HIV standard genotyping among antiretroviral-naive individuals with unknown duration of infection.
Publication TypeJournal Article
Year of Publication2007
AuthorsSmith D, Moini N, Pesano R, Cachay E, Aiem H, Lie Y, Richman D, Little S
JournalClin Infect Dis
Volume44
Issue3
Pagination456-8
Date Published2007 Feb 1
ISSN1537-6591
KeywordsAnti-HIV Agents, California, Drug Resistance, Multiple, Viral, Female, Genotype, HIV, HIV Infections, Humans, Male, Patient Care Planning, Prevalence, Treatment Outcome
Abstract

In clinical settings, we have found a high rate of human immunodeficiency virus (HIV) drug resistance among antiretroviral-naive patients for whom the duration of infection was unknown. These high rates were most likely the result of both transmitted resistance and informal antiretroviral use, and they suggest that routine resistance testing among antiretroviral-naive patients would be a cost-effective clinical practice.

DOI10.1086/510748
Alternate JournalClin. Infect. Dis.
PubMed ID17205459
Grant ListAI 36214 / AI / NIAID NIH HHS / United States
AI043638 / AI / NIAID NIH HHS / United States
AI047745 / AI / NIAID NIH HHS / United States
AI07384 / AI / NIAID NIH HHS / United States
AI27670 / AI / NIAID NIH HHS / United States
AI29164 / AI / NIAID NIH HHS / United States
AI55276 / AI / NIAID NIH HHS / United States
U01AI38858 / AI / NIAID NIH HHS / United States