Title | HIV-1 drug resistance genotype results in patients with plasma samples with HIV-1 RNA levels less than 75 copies/mL. |
Publication Type | Journal Article |
Year of Publication | 2006 |
Authors | Mitsuya Y, Winters MA, W Fessel J, Rhee S-Y, Slome S, Flamm J, Horberg M, Hurley L, Klein D, Shafer RW |
Journal | J Acquir Immune Defic Syndr |
Volume | 43 |
Issue | 1 |
Pagination | 56-9 |
Date Published | 2006 Sep |
ISSN | 1525-4135 |
Keywords | Anti-HIV Agents, Drug Resistance, Viral, Genotype, HIV Infections, HIV-1, Humans, Phylogeny, RNA, Viral, Viral Load |
Abstract | HIV-1 genotypic resistance test results were obtained on clinical samples from 116 patients with plasma HIV-1 RNA levels of less than 75 copies/mL. Genotype validity was confirmed in 49 of 50 patients with a previous or follow-up genotype. The belief that genotypic resistance testing is unreliable in samples with low-level viremia should be reassessed. |
DOI | 10.1097/01.qai.0000232609.99705.a2 |
Alternate Journal | J. Acquir. Immune Defic. Syndr. |
PubMed ID | 16885777 |
PubMed Central ID | PMC2547468 |
Grant List | R01 AI046148 / AI / NIAID NIH HHS / United States R01 AI046148-08 / AI / NIAID NIH HHS / United States |