Studies that are enrolling

A5378: Safety & Virologic Effect of HIV-1 Specific Broadly Neutralizing Human MAbs (VRC01LS&VRC07523LS)

VRC 607/ACTG A5378: A Phase I, Single-Dose Study of the Safety and Virologic Effect of an HIV-1-Specific Broadly Neutralizing Human Monoclonal Antibody, VRC-HIVMAB080-00-AB (VRC01LS) or VRC-HIVMAB075-00-AB (VRC07-523LS), Administered Intravenously to HIV-Infected Adults

A5321: ACTG HIV Reservoirs Cohort (AHRC)

ACTG A5321: Decay of HIV-1 Reservoirs in Subjects on Long-Term Antiretroviral Therapy: The ACTG HIV Reservoirs Cohort (AHRC) Study  

August 2018 Edition of AHRC Newsletter

A5354: Early ART in Acute HIV

ACTG A5354/EARLIER: Effect of Antiretroviral Treatment Initiated During Acute HIV-1 Infection on Measures of HIV-1 Persistence and on HIV-1-Specific Immune Responses

Study Description
This study will include people who have very recently been infected with HIV and will start anti-HIV (antiretroviral) drugs right away to see how this may change HIV’s impact on the body. 

A5341s: A5321 Sampling Substudy

A5341s: Longitudinal Sampling Substudy of A5321

Why is this substudy, A5341s, being done?

This substudy will compare samples from different reservoirs to learn more about the following:

A5332: Randomized Trial to Prevent Vascular Events in HIV (REPRIEVE)

Treatment Category

Treatment Experienced

Study Description

REPRIEVE (A5332) is a large double-blind, randomized, placebo-controlled study of pitavastatin or placebo for about 72 months. The trial is testing the effect of statin therapy on preventing heart disease and death in HIV-infected persons on HIV medications who do not meet guidelines for starting statins.      

A5243: Non-US Genomic Sampling

Plan for Obtaining Human Biological Samples at Non-U.S. Clinical Research Sites for Currently Unspecified Genetic Analyses

Study Description

This is a study to collect blood and saliva samples from former and current participants in AIDS Clinical Trial Group (ACTG) studies at non-U.S. sites.

Why is this study being done?

All samples will be stored for future HIV-related genetic testing. Any use of these samples will have to be approved both by the ACTG and by site Ethics Committees.

A5128: US Genomic Sampling

Plan for Obtaining Informed Consent to use Stored Human Biological Materials (HBM) for Currently Unspecified Analysis.

Study Description

Informed consent to use stored specimens for currently unspecified/ genetic analyses.

Why is this study being done?

To develop a standard operating procedure to establish a storage bank for specimens for future genetic (DNA) analyses.

Who can join?

Anyone enrolled in an ACTG study.

What do I need to do in the study?

Blood stored for future testing.

Subscribe to RSS - Enrolling