Studies that are enrolling

A5300B: MDR TB Households

A5300B/I2003B/PHOENIx: Protecting Households On Exposure to Newly Diagnosed Index Multidrug-Resistant Tuberculosis Patients (PHOENIx MDR-TB)

Treatment Category: Tuberculosis

Study Description

A5375: Optimize LNG EC

ACTG A5375: An Open-Label, Phase II Pharmacokinetic Study to Evaluate Double-Dose Levonorgestrel Emergency Contraception in Combination with Efavirenz-Based Antiretroviral Therapy or Rifampicin-Containing Anti-Tuberculosis Therapy

Treatment Category: Treatment Experienced

A5359: The LATITUDE Study

ACTG A5359: Long-Acting Antiretroviral Therapy in Non-adherent Persons Living with HIV (PLWH)
Treatment Category:  Treatment Experienced

Study Description

This four-step study compares Long-Acting (LA) Injectable Antiretroviral Therapy (ART) to standard of care (SOC) oral ART in previously non-adherent individuals.

A5354: Early ART in Acute HIV

ACTG A5354/EARLIER: Effect of Antiretroviral Treatment Initiated During Acute HIV-1 Infection on Measures of HIV-1 Persistence and on HIV-1-Specific Immune Responses

Study Description
This study will include people who have very recently been infected with HIV and will start anti-HIV (antiretroviral) drugs right away to see how this may change HIV’s impact on the body. 

A5341s: A5321 Sampling Substudy

A5341s: Longitudinal Sampling Substudy of A5321

Why is this substudy, A5341s, being done?

This substudy will compare samples from different reservoirs to learn more about the following:

A5243: Non-US Genomic Sampling

Plan for Obtaining Human Biological Samples at Non-U.S. Clinical Research Sites for Currently Unspecified Genetic Analyses

Study Description

This is a study to collect blood and saliva samples from former and current participants in AIDS Clinical Trial Group (ACTG) studies at non-U.S. sites.

Why is this study being done?

All samples will be stored for future HIV-related genetic testing. Any use of these samples will have to be approved both by the ACTG and by site Ethics Committees.

A5128: US Genomic Sampling

Plan for Obtaining Informed Consent to use Stored Human Biological Materials (HBM) for Currently Unspecified Analysis.

Study Description

Informed consent to use stored specimens for currently unspecified/ genetic analyses.

Why is this study being done?

To develop a standard operating procedure to establish a storage bank for specimens for future genetic (DNA) analyses.

Who can join?

Anyone enrolled in an ACTG study.

What do I need to do in the study?

Blood stored for future testing.

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